Filters
Interim results of REGENERATE* trial highlight the ability of experimental noninvasive tests to evaluate treatment response in adults with NASH** and advanced liver fibrosis who are receiving obeticholic acid (OCA).
Two doses of the novel potassium‐competitive acid blocker tegoprazan show comparable healing effects on gastric ulcers as lansoprazole, while having a favourable safety profile, according to the results of a phase III trial.
The novel switch-control tyrosine kinase inhibitor ripretinib delivered a clinically meaningful benefit for patients with gastrointestinal stromal tumours (GISTs) following crossover from placebo, and had a safety profile consistent with that observed in the double-blind phase, according to the results of the crossover analysis of the INVICTUS trial presented at ESMO GI 2020.
A trivalent vaccine against hepatitis (hep B) is safe and effectively elicits robust immune response compared with a monovalent Hep B vaccine, according to the PROTECT and CONSTANT studies presented during the 2020 digital ILC.
A healthy lifestyle pattern, especially maintaining a healthy weight, may lower the risk of developing symptomatic gallstone diseases, as indicated by findings from two large prospective studies.
Older patients (aged ≥65 years) with unresectable hepatocellular carcinoma (HCC) may derive greater survival benefit with an atezolizumab + bevacizumab combination compared with sorafenib, according to results of a subgroup analysis of the IMbrave150 trial presented at ESMO GI 2020.
Drinking coffee, tea, or soda may trigger gastroesophageal reflux, whereas water, juice, or milk does not, according to a study.
Safety data from the phase III IMbrave150 trial reinforce the previously reported favourable safety profile of atezolizumab-bevacizumab compared with sorafenib for unresectable hepatocellular carcinoma (HCC).
In patients with advanced hepatocellular carcinoma (HCC), first-line treatment with nivolumab may confer greater overall survival (OS) than sorafenib, according to updated results of the phase III CheckMate 459* study.
Hope for a hepatitis B virus cure becomes manifest as multiple drugs from recent clinical trials show potential in transforming the battle against the disease.
