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Psilocybin may help ease depression symptoms
Treatment with psilocybin significantly improves the symptoms of depression, particularly when using self-report scales and when individuals have used psychedelics in the past, results of a systematic review and meta-analysis have shown.

Dequalinium chloride works as well as metronidazole for bacterial vaginosis
In the treatment of bacterial vaginosis, dequalinium chloride is noninferior to metronidazole, with similarly high cure rates but better tolerability and fewer adverse events, according to a phase IV study.

Patritumab deruxtecan may improve survival in EGFR-mutated NSCLC
Treatment with patritumab deruxtecan (HER3-DXd) confers survival benefits on patients with epidermal growth factor receptor (EGFR)-mutated nonsmall-cell lung cancer (NSCLC) following EGFR tyrosine kinase inhibitor (TKI) and platinum-based chemotherapy, results of a phase I study have shown.

Solo ticagrelor after 1-month DAPT: Is it time to change practice?
Dropping aspirin for ticagrelor monotherapy 1 month after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) is as good as dual antiplatelet therapy (DAPT) in the ULTIMATE-DAPT* trial presented at ACC.24.

Vonoprazan-amoxicillin on par with quadruple therapy for H pylori eradication
Dual therapy with vonoprazan and amoxicillin (VA-dual) for 10 days results in a 90.8-percent eradication rate of Helicobacter pylori (H pylori) and fewer adverse events (AEs) compared with the standard 14-day bismuth-based quadruple therapy (B-quadruple), a study has shown.

Olanzapine vs fosaprepitant: Which is better for CINV prevention?
Olanzapine appears to be just as effective as fosaprepitant, a neurokinin-1 receptor antagonist (NK1-RA), in controlling chemotherapy-induced nausea and vomiting (CINV) in patients with gynaecologic malignancies who were receiving carboplatin/paclitaxel chemotherapy every 3 weeks, a prospective study presented at SGO 2024 suggests. However, the former trumps the latter in terms of cost effectiveness.



