News & Updates

In women undergoing autologous in vitro fertilization (IVF) for fertility treatment, ovulatory suppression with medroxyprogesterone acetate proves effective, with cycle and reproductive outcomes similar to that with gonadotropin-releasing hormone (GnRH) antagonist and the advantage of being cheaper, according to a study.

Oral lasofoxifene at either 0.25 or 0.5 mg daily confers benefits on genitourinary syndrome of menopause, with pooled data from two phase III trials showing significant improvements in vaginal signs or symptoms while having a favourable safety profile.

Children who were exposed antenatally to betamethasone as opposed to placebo are not necessarily at a disadvantage in terms of neurodevelopment outcomes, as shown in a follow-up to the Antenatal Late Preterm Steroids (ALPS) trial.

Giving oral anticoagulants to patients with device-detected atrial fibrillation (AF) and multiple comorbidities does not necessarily help lower the rate of cardiovascular events, according to a subgroup analysis of the NOAH-AFNET 6 trial.

The use of diltiazem, especially at doses exceeding 120 mg/d, appears to contribute to a heightened risk of serious bleeding compared with metoprolol in patients with atrial fibrillation (AF) who are receiving oral anticoagulant therapy, according to a retrospective cohort study.

In the placebo-controlled ORBITA-COSMIC* trial, an implantable coronary sinus reducer (CSR) does not increase transmural myocardial perfusion, but it reduces the frequency of angina and improves quality of life (QoL) in patients with no further antianginal options.

Children of mothers who took n‒3 long-chain polyunsaturated fatty acid (LCPUFA) supplements during pregnancy tend to have an increased body mass index (BMI) at age 10 years, a higher risk of being overweight, and greater fat percentage and metabolic syndrome score, a study has shown.