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SKYSCRAPER-08 hits mark in ESCC with dual checkpoint inhibition + doublet chemo

16 Feb 2024 by

In Asian patients with esophageal squamous cell carcinoma (ESCC), adding the TIGIT inhibitor tiragolumab and PD-L1 inhibitor atezolizumab to chemotherapy improved all outcomes in the phase III SKYSCRAPER-08 trial.

SKYSCRAPER-08 hits mark in ESCC with dual checkpoint inhibition + doublet chemo

16 Feb 2024

Original New Drug Application Approvals by US FDA (01-15 February 2024)

16 Feb 2024

New drug applications approved by US FDA as of 01-15 February 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 February 2024)

16 Feb 2024

Potassium-competitive acid blockers linked to gastric cancer risk after H pylori eradication

15 Feb 2024

Exposure to potassium-competitive acid blockers (PCABs) may heighten the risk of developing gastric cancer after successful treatment for Helicobacter pylori infection, according to a study.

Potassium-competitive acid blockers linked to gastric cancer risk after H pylori eradication

15 Feb 2024

High oxytocin dose helps reduce postpartum haemorrhage

15 Feb 2024 by

Use of high-dose oxytocin postpartum appears to result in reduced rates of postpartum haemorrhage (PPH) when compared with traditional doses, as shown in a study presented at SMFM 2024.

High oxytocin dose helps reduce postpartum haemorrhage

15 Feb 2024

$Testosterone treatment offers no protection against fractures in men with hypogonadism$

Testosterone treatment offers no protection against fractures in men with hypogonadism

14 Feb 2024

Testosterone treatment does not help lower the incidence of clinical fractures in middle-aged and older men with hypogonadism, according to a study.

Testosterone treatment offers no protection against fractures in men with hypogonadism

14 Feb 2024

Mupirocin proves safety as prevention for catheter-related infections

14 Feb 2024 by

Use of topical mupirocin prophylaxis is feasible and has an acceptable safety profile for the long-term prevention of indwelling pleural catheter (IPC)- or indwelling peritoneal catheter (IPeC)-related infections, results of a pilot study have shown.

Mupirocin proves safety as prevention for catheter-related infections

14 Feb 2024

Semaglutide for weight management beneficial to Asians with overweight, obesity

14 Feb 2024

Treatment with semaglutide induces weight loss in Asians with overweight or obesity, regardless of the presence of type 2 diabetes, according to the phase IIIa STEP 7 study.

Semaglutide for weight management beneficial to Asians with overweight, obesity

14 Feb 2024

Risk of PFCs lower with anti-TNF therapy if given early

14 Feb 2024 by

Early treatment with tumour necrosis factor (TNF) inhibitors lowers the risk of perianal fistulizing complications (PFCs) in children and teens compared with no immunosuppression or immunomodulators without TNF inhibitors in a post-hoc analysis of a prospective observational study.

Risk of PFCs lower with anti-TNF therapy if given early

14 Feb 2024

Lying flat prior to thrombectomy good for LVO stroke

14 Feb 2024 by

Positioning patients with large vessel occlusion (LVO) stroke flat on the bed prior to thrombectomy helps improve neurologic outcomes in the randomized controlled ZODIAC* trial.

Lying flat prior to thrombectomy good for LVO stroke

14 Feb 2024

Serious infections prevalent in RTX-treated patients with SLE

13 Feb 2024

A recent study has reported the prevalence of serious infection (SI) among patients with systemic lupus erythematosus (SLE) following treatment with rituximab (RTX).

Serious infections prevalent in RTX-treated patients with SLE

13 Feb 2024

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SKYSCRAPER-08 hits mark in ESCC with dual checkpoint inhibition + doublet chemo

SKYSCRAPER-08 hits mark in ESCC with dual checkpoint inhibition + doublet chemo

Original New Drug Application Approvals by US FDA (01-15 February 2024)

Original New Drug Application Approvals by US FDA (01-15 February 2024)

Potassium-competitive acid blockers linked to gastric cancer risk after H pylori eradication

Potassium-competitive acid blockers linked to gastric cancer risk after H pylori eradication

High oxytocin dose helps reduce postpartum haemorrhage

High oxytocin dose helps reduce postpartum haemorrhage

Testosterone treatment offers no protection against fractures in men with hypogonadism

Testosterone treatment offers no protection against fractures in men with hypogonadism

Mupirocin proves safety as prevention for catheter-related infections

Mupirocin proves safety as prevention for catheter-related infections

Semaglutide for weight management beneficial to Asians with overweight, obesity

Semaglutide for weight management beneficial to Asians with overweight, obesity

Risk of PFCs lower with anti-TNF therapy if given early

Risk of PFCs lower with anti-TNF therapy if given early

Lying flat prior to thrombectomy good for LVO stroke

Lying flat prior to thrombectomy good for LVO stroke

Serious infections prevalent in RTX-treated patients with SLE

Serious infections prevalent in RTX-treated patients with SLE