News &amp; Updates

Inactivated quadrivalent influenza vaccine (split virion) – Suspension for injection

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Inclisiran – Solution for injection

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Dupilumab shows benefit in young children with EoE

15 Jun 2023 by

Treatment with dupilumab significantly improves histologic and endoscopic measures of eosinophilic esophagitis (EoE) in young children aged 1–11 years, according to the phase III EoE KIDS trial presented at ESPGHAN 2023.

Dupilumab shows benefit in young children with EoE

Sacubitril/valsartan outdoes valsartan on ventricular remodeling in perimenopausal hypertension

14 Jun 2023

Treatment with sacubitril/valsartan appears to be better than valsartan alone in reversing ventricular remodeling in perimenopausal hypertensive women, suggests a study.

Sacubitril/valsartan outdoes valsartan on ventricular remodeling in perimenopausal hypertension

14 Jun 2023

Methotrexate poses no risk for men seeking parenthood

Treatment with methotrexate (MTX) does not appear to be associated with testicular toxicity, according to the results of the iFAME-MTX study, dispelling concerns about the effect of the drugs among men wishing to become a parent and their clinicians.

Methotrexate poses no risk for men seeking parenthood

Loperamide, mitragynine linked to ventricular arrhythmias

Use of nonprescription drugs loperamide and mitragynine appears to contribute to the risk of life-threatening ventricular arrhythmia, reports a study in North America.

Loperamide, mitragynine linked to ventricular arrhythmias

BNT162b2 booster protects against COVID-19 infection, hospitalization in adolescents

In a national cohort study in Singapore, a booster dose of BNT162b2 maintained individual protection against severe COVID-19 disease among adolescents aged 12–17 years.

BNT162b2 booster protects against COVID-19 infection, hospitalization in adolescents

13 Jun 2023

COVID-19 boosters do not increase miscarriage risk

A case-control surveillance study has found no link between monovalent COVID-19 boosters and miscarriage before 20 weeks of pregnancy.

COVID-19 boosters do not increase miscarriage risk

Add-on L. reuteri mitigates diarrhoea risk in children on antibiotics

Adding the probiotic Limosilactobacillus reuteri (L. reuteri) DSM 17938 to antibiotic therapy significantly reduced the incidence of antibiotic-associated diarrhoea (AAD) in children with acute otitis media or acute bacterial sinusitis in the PEARL study presented at ESPGHAN 2023.

Add-on L. reuteri mitigates diarrhoea risk in children on antibiotics

Bivalent mRNA-1273.214 vaccine safe, immunogenic in children

Interim results from the ongoing Study 306, a phase III open-label trial, show improved immunogenicity and safety of the bivalent Omicron-containing mRNA-1273.214 vaccine in children 6 months to 5 years of age, both as a primary series and a booster.

Bivalent mRNA-1273.214 vaccine safe, immunogenic in children