News & Updates

Inflammatory biomarkers may pinpoint people at high-risk of psychiatric disorders

Inflammatory biomarkers such as leukocytes, haptoglobin, C-reactive protein (CRP), and immunoglobulin G (IgG) appear to be associated with a subsequent risk of psychiatric disorders and may thus aid in identifying high-risk populations, according to a study.

Mirtazapine does not alleviate severe breathlessness in COPD, ILD

Treatment with mirtazapine to improve severe breathlessness in patients with chronic obstructive pulmonary disease (COPD), interstitial lung diseases (ILD), or both falls flat, with the use of the medication even associated with adverse reactions, as shown in a phase III study.

Meta-analysis provides safety reassurance for metformin use during pregnancy

Antenatal exposure to metformin does not appear to harm neurodevelopmental outcomes in children, according to the results of a meta-analysis.

Cardiopulmonary exercise testing can predict outcome in paediatric CHD

Reduced exercise capacity at a young age appears to be associated with a higher likelihood of future cardiovascular events in paediatric patients with congenital heart defects (CHDs), according to a study.

NALIRIFOX improves survival in older patients with mPDAC

Treatment with liposomal irinotecan plus 5-fluorouracil, leucovorin, and oxaliplatin (NALIRIFOX) improved overall survival (OS) and progression-free survival (PFS) in patients aged ≥65 years with metastatic pancreatic ductal adenocarcinoma (mPDAC) compared with gemcitabine plus nab-paclitaxel (Gem+NabP), according to a post hoc analysis of the phase III NAPOLI 3 trial presented at ESMO GI 2024.

Hidradenitis suppurativa less likely to occur among ex-smokers

Quitting smoking and maintaining a smoke-free status help prevent hidradenitis suppurativa (HS) when compared with continuous smoking, according to a large study.