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Etavopivat reduces VOCs in patients with sickle cell disease

29 Jan 2025 by

Once-daily treatment with etavopivat results in lower rates of annualized vaso-occlusive crises (VOCs) in patients with sickle cell disease (SCD) compared with placebo, according to the HIBISCUS trial presented at ASH 2024.

Etavopivat reduces VOCs in patients with sickle cell disease

29 Jan 2025

CKD predicts cardiac, cerebral events risk in patients with chronic coronary syndrome

28 Jan 2025

Among patients with chronic coronary syndrome, those with chronic kidney disease (CKD) at baseline are at increased risk of major adverse cardiac and cerebral events (MACCE), according to data from the REAL‐CAD* study.

CKD predicts cardiac, cerebral events risk in patients with chronic coronary syndrome

28 Jan 2025

Undernutrition impairs measles, tetanus vax responses in children

28 Jan 2025 by

Children who are undernourished may have a compromised immune response to certain vaccines, and this impaired response can contribute to the burden of vaccine-preventable diseases, according to the VHEMBE* South African birth cohort study.

Undernutrition impairs measles, tetanus vax responses in children

28 Jan 2025

PegIFN-α-2a lowers relapse in HBeAg-negative patients after NUC cessation

28 Jan 2025

Switching treatment from nucleo(s)tide analogue (NUC) to pegylated interferon alpha-2a (PegIFN-α-2a) for 48 weeks results in a significant decrease in virological relapse rates as well as higher hepatitis B surface antigen (HBsAg) loss rates when compared with NUC treatment cessation alone in patients with HBeAg-negative chronic hepatitis B, reports a study.

PegIFN-α-2a lowers relapse in HBeAg-negative patients after NUC cessation

28 Jan 2025

Tremelimumab plus durvalumab improves survival in Asians with unresectable HCC

28 Jan 2025 by

A single tremelimumab regular interval durvalumab (STRIDE) provides survival benefits to Asian patients with unresectable hepatocellular carcinoma (HCC), as shown by the results of the HIMALAYA study.

Tremelimumab plus durvalumab improves survival in Asians with unresectable HCC

28 Jan 2025

Early menarche predicts hypertension in premenopausal women

28 Jan 2025

Early menarche is significantly associated with a higher chance of developing hypertension, specifically in women of reproductive age, suggests a study.

Early menarche predicts hypertension in premenopausal women

28 Jan 2025

High-fibre diets in blood cancers: What do we know?

28 Jan 2025 by

High-fibre diets improved blood cancer outcomes in two studies reported at ASH 2024.

High-fibre diets in blood cancers: What do we know?

28 Jan 2025

Study finds DNA methylation profile for early breast cancer detection

28 Jan 2025 by

Researchers from Singapore have found a whole blood-based DNA methylation biomarker profile that effectively distinguishes breast cancer patients from healthy controls.

Study finds DNA methylation profile for early breast cancer detection

28 Jan 2025

Baricitinib cuts need for oral steroids in polymyalgia rheumatica

28 Jan 2025

In the treatment of patients with polymyalgia rheumatica, the Janus kinase 1/2 inhibitor baricitinib helps reduce the need to take oral glucocorticoids to have low disease activity while having no new safety signals, according to data from the randomized, double-blind BACHELOR trial.

Baricitinib cuts need for oral steroids in polymyalgia rheumatica

28 Jan 2025

MAGIC database facilitates understanding of early-life gut microbiome dynamics

28 Jan 2025 by

The Metagenome-Assembled Genome Inventory for Children (MAGIC) database, which contains 20,172 global gut metagenomes from humans aged 0–7 years, characterizes the bacteriome and virome diversity of the global gut microbiome in early life.

MAGIC database facilitates understanding of early-life gut microbiome dynamics

28 Jan 2025

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Etavopivat reduces VOCs in patients with sickle cell disease

Etavopivat reduces VOCs in patients with sickle cell disease

CKD predicts cardiac, cerebral events risk in patients with chronic coronary syndrome

CKD predicts cardiac, cerebral events risk in patients with chronic coronary syndrome

Undernutrition impairs measles, tetanus vax responses in children

Undernutrition impairs measles, tetanus vax responses in children

PegIFN-α-2a lowers relapse in HBeAg-negative patients after NUC cessation

PegIFN-α-2a lowers relapse in HBeAg-negative patients after NUC cessation

Tremelimumab plus durvalumab improves survival in Asians with unresectable HCC

Tremelimumab plus durvalumab improves survival in Asians with unresectable HCC

Early menarche predicts hypertension in premenopausal women

Early menarche predicts hypertension in premenopausal women

High-fibre diets in blood cancers: What do we know?

High-fibre diets in blood cancers: What do we know?

Study finds DNA methylation profile for early breast cancer detection

Study finds DNA methylation profile for early breast cancer detection

Baricitinib cuts need for oral steroids in polymyalgia rheumatica

Baricitinib cuts need for oral steroids in polymyalgia rheumatica

MAGIC database facilitates understanding of early-life gut microbiome dynamics

MAGIC database facilitates understanding of early-life gut microbiome dynamics