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RNAi agent RG6346 shows promise for treatment of chronic HBV infection
A first-in-human randomized, phase I study has provided evidence to support the clinical development of RG6346 as a therapeutic regimen for chronic hepatitis B virus (HBV) infection (CHB), with the goal of sustained hepatitis B surface antigen (HBsAg) loss in CHB patients.

Which factors predict recurrence of RA-related organizing pneumonia?
The recurrence rate of organizing pneumonia (OP) associated with rheumatoid arthritis (RA) is high, but OP does not appear to contribute to RA exacerbation, suggests a study. Several factors predicting OP recurrence have been identified, such as smoking and lower age at OP onset.

Multimodal intervention reduces second-line antibiotic prescriptions for UTI
A multimodal intervention applied in general practice results in a significant decrease in antibiotic prescribing and an increase in guideline adherence among women with uncomplicated urinary tract infection (UTI), a study has shown.





