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Novel mRNA-based vaccine prevents flu infection in adults

17 Nov 2025 by

The novel mRNA-based influenza vaccine mRNA-1010 has demonstrated superior efficacy over its standard-dose (SD) comparator in preventing RT-PCR–confirmed protocol-defined influenza disease in adults aged 50 years and above, reports a study presented at IDWeek 2025.

Novel mRNA-based vaccine prevents flu infection in adults

17 Nov 2025

Depot medroxyprogesterone acetate linked to increased meningioma risk

16 Nov 2025

Women using depot medroxyprogesterone acetate are at heightened risk of subsequent meningioma diagnosis, although the overall clinical risk is low, according to a retrospective study.

Depot medroxyprogesterone acetate linked to increased meningioma risk

16 Nov 2025

Major bleeding risk higher with ticagrelor vs clopidogrel in multiethnic ACS patients

16 Nov 2025 by

For multiethnic Southeast Asian patients with acute coronary syndrome (ACS), bleeding outcomes including BARC type 3 bleeding appear to be less favourable with ticagrelor than with clopidogrel, as shown in a retrospective study from Singapore.

Major bleeding risk higher with ticagrelor vs clopidogrel in multiethnic ACS patients

16 Nov 2025

Infection risk higher in adalimumab users with HS vs psoriasis

16 Nov 2025

Among adults receiving adalimumab treatment, those with hidradenitis suppurativa appear to be at greater risk of infection than their psoriasis counterparts, as reported in a retrospective study.

Infection risk higher in adalimumab users with HS vs psoriasis

16 Nov 2025

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

15 Nov 2025 by

Receipt of messenger RNA (mRNA)-based COVID-19 vaccine during pregnancy does not appear to be associated with an increased risk of any major congenital malformations, according to new research from France.

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

15 Nov 2025

DS-5670d vaccine against COVID-19 not inferior to BNT162b2

14 Nov 2025 by

A single dose of the omicron XBB.1.5-targeting COVID-19 mRNA vaccine DS-5670d demonstrates immunogenic non-inferiority to BNT162b2 in individuals with or without a history of prior SARS-CoV-2 infection or COVID-19 vaccination, reports a study.

DS-5670d vaccine against COVID-19 not inferior to BNT162b2

14 Nov 2025

Telitacicept beneficial in childhood-onset SLE

14 Nov 2025

In the management of patients with childhood-onset systemic lupus erythematosus (cSLE), combining telitacicept with standard of care (SoC) appears to reduce disease activity, steroid exposure, and immunological marker concentrations, effects comparable to those observed with belimumab, according to a study.

Telitacicept beneficial in childhood-onset SLE

14 Nov 2025

Cenobamate helps with focal seizures in Asians

13 Nov 2025

Cenobamate helps reduce focal seizure in a dose-dependent manner in Asian patients, while being generally well tolerated, according to a study.

Cenobamate helps with focal seizures in Asians

13 Nov 2025

Durvalumab plus chemo delivers sustained survival benefits in advanced BTC

13 Nov 2025 by

A 3-year update from the phase III TOPAZ-1 study has shown sustained survival benefit and manageable safety with durvalumab plus gemcitabine and cisplatin (GemCis) relative to placebo among patients with advanced biliary tract cancer (BTC).

Durvalumab plus chemo delivers sustained survival benefits in advanced BTC

13 Nov 2025

Rivaroxaban may prevent PHT-related complications in cirrhosis

13 Nov 2025

Treatment with rivaroxaban appears to improve portal hypertension (PHT)-related complications without increasing the risk of major bleeding in patients with cirrhosis and moderate liver dysfunction, a study has shown.

Rivaroxaban may prevent PHT-related complications in cirrhosis

13 Nov 2025

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Novel mRNA-based vaccine prevents flu infection in adults

Novel mRNA-based vaccine prevents flu infection in adults

Depot medroxyprogesterone acetate linked to increased meningioma risk

Depot medroxyprogesterone acetate linked to increased meningioma risk

Major bleeding risk higher with ticagrelor vs clopidogrel in multiethnic ACS patients

Major bleeding risk higher with ticagrelor vs clopidogrel in multiethnic ACS patients

Infection risk higher in adalimumab users with HS vs psoriasis

Infection risk higher in adalimumab users with HS vs psoriasis

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

Large French study clears mRNA-based COVID-19 vaccines of teratogenic risk

DS-5670d vaccine against COVID-19 not inferior to BNT162b2

DS-5670d vaccine against COVID-19 not inferior to BNT162b2

Telitacicept beneficial in childhood-onset SLE

Telitacicept beneficial in childhood-onset SLE

Cenobamate helps with focal seizures in Asians

Cenobamate helps with focal seizures in Asians

Durvalumab plus chemo delivers sustained survival benefits in advanced BTC

Durvalumab plus chemo delivers sustained survival benefits in advanced BTC

Rivaroxaban may prevent PHT-related complications in cirrhosis

Rivaroxaban may prevent PHT-related complications in cirrhosis