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SG kids prone to multisystem inflammatory syndrome amid high COVID-19 transmission

04 Jan 2023 by

Children in Singapore are at risk of developing multisystem inflammatory syndrome (MIS-C), especially due to the increased community transmission of COVID-19 in 2021, according to a study. MIS-C incidence may also intensify with the arrival of new variants of concern (VOCs) and relaxation of pandemic restrictions.

04 Jan 2023

Procalcitonin-based algorithm reduces unnecessary antibiotic use in acute pancreatitis

01 Jan 2023 by

A procalcitonin-guided algorithm could reduce the unnecessary use of antibiotics in patients with acute pancreatitis, according to results of the PROCAP trial.

01 Jan 2023

Original New Drug Application Approvals by US FDA (16-31 December 2022)

31 Dec 2022

New drug applications approved by US FDA as of 16 - 31 December 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

31 Dec 2022

Serine protease inhibition shows promise in COVID-19

23 Dec 2022 by

The serine protease inhibitor upamostat appears to be beneficial in the treatment of COVID-19 outpatients, being generally tolerable and bringing a rapid resolution of severe symptoms while reducing the incidence of new ones, according to the results of a pilot study.

23 Dec 2022

Bepirovirsen shows promise in controlling chronic HBV infection

19 Dec 2022 by

Weekly bepirovirsen treatment may help reduce HBsAg* and hepatitis B virus (HBV) DNA levels in patients with chronic HBV infection, the phase IIb B-Clear study showed.

19 Dec 2022

One in eight adults experiences long COVID

18 Dec 2022 by

One in every eight individuals who has experienced COVID-19 may have persistent symptoms 3–5 months post-infection, according to an observational study from the Netherlands.

18 Dec 2022

Multipathogen testing an essential part of Test-Target-Treat strategy for respiratory illnesses

16 Dec 2022 by

At a recent webinar, experts discussed the paradigm shift in respiratory illnesses and treatment practices as the COVID-19 pandemic transitions to an endemic phase. The late Dr Mohan Ravuru, Physician Researcher and former Asia Pacific Medical Director, Abbott, Dr Johnny Sinon, Senior Emergency Physician from Makati Medical Center, Philippines, and Associate Professor Nuntra Suwantarat, Infectious Disease Specialist, from Chulabhorn International College of Medicine, Thammasat University, Thailand, delivered informative presentations and engaged the audience through a stimulating panel discussion.

Among the topics covered were the ‘immunity debt’ phenomenon leading to potential epidemics, challenges in the differential diagnosis of COVID-19 and influenza, and the importance of point-of-care, multipathogen testing as a part of the Test-Target-Treat strategy in respiratory diseases.

16 Dec 2022

COVID-19 vaccination boosts mental wellbeing during pandemic

15 Dec 2022

Individuals who have received one or two doses of the COVID-19 vaccinations experience improved mental wellbeing during the pandemic, reports a recent Japan study.

15 Dec 2022

Pregnant women in ICU for COVID-19 more deprived, less vaccinated

12 Dec 2022

Pregnant or recently pregnant women who needed intensive care admission due to COVID-19 tend to live in poorer areas and are less likely to have been vaccinated, a recent study has found.

12 Dec 2022

E. coli, S. agalactiae afflict most infants with invasive bacterial infections

10 Dec 2022

From 2006 to 2020, the most common invasive bacterial infections (IBIs) among infants <3 months of age are S. agalactiae, E. coli, and S. aureus, reveals a recent study in Korea. In addition, an increasing trend of S. agalactiae has been seen.