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Mirtazapine of no benefit for agitated behaviours in dementia
Results of a randomized, double-blind, placebo-controlled trial show no benefit with mirtazapine, given with normal clinical care, for treatment of clinically significant agitation in patients with dementia compared with placebo, with a potentially higher mortality observed with the use of mirtazapine.

3 measures of insulin resistance predict depression
Three surrogate measures of insulin resistance are positively associated with incident major depressive disorder among adults with no history of depression or anxiety disorder, results of the Netherlands Study of Depression and Anxiety (NESDA) have shown. Moreover, the development of prediabetes between study enrolment and 2-year visit also predicts incident major depressive disorder.

Reopening after COVID-19 lockdown triggers shifts in sleep patterns, mental health
Reopening workplaces and establishments after the lifting of coronavirus disease 2019 (COVID-19) lockdowns leads to an increase in physical activity as well as notable shifts in sleep patterns and mental wellbeing, according to a recent Singapore study.


