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Catheter-directed thrombolysis trumps systemic anticoagulation for submassive pulmonary embolism
Catheter-directed thrombolysis (CDT) is superior to systemic anticoagulation (SA) for the treatment of submassive pulmonary embolism (sPE), leading to better mortality rates without additional safety signals, a recent meta-analysis has found.

Response analysis further establishes tezepelumab benefit in severe uncontrolled asthma
Adolescents and adults with severe uncontrolled asthma while on inhaled corticosteroids (ICS) had greater responses to the human monoclonal antibody tezepelumab than placebo, according to prespecified exploratory results of the phase III NAVIGATOR trial.

Antibody responses to COVID-19 vaccines in older people: Recent evidence & local data
Older adults have weaker antibody responses to two doses of COVID-19 vaccines [ie, mRNA-based BNT162b2 vaccine and inactivated CZ02 vaccine] vs younger individuals, but a booster dose mounts SARS-CoV-2 neutralization activities to a high level, according to data presented at AIM 2022.





