News & Updates

The rates of anaphylaxis among commonly used intravenous (IV) iron formulations are low, but those for iron dextran and ferumoxytol are three- to eightfold higher compared to iron sucrose, results of a recent study have shown.

In patients with advanced anaplastic lymphoma kinase-positive non-small cell lung cancer (ALK+ NSCLC) who were ALK inhibitor-naïve, brigatinib showed superior efficacy and safety over crizotinib, according to the final results of the phase III ALTA-1L* trial presented at ELCC 2022.

Parathyroidectomy (PTX) seems ineffective at reducing morbidity or mortality in patients with mild primary hyperparathyroidism (PHPT) relative to observation without intervention, suggests a study. For at least a decade, observation has seen no evidence of adverse effects regarding mortality, fractures, cancer, cardiovascular (CV) and cerebrovascular (CBV) events, or renal morbidities.

In women with platinum-sensitive relapsed ovarian cancer without a deleterious or suspected deleterious germline BRCA1/BRCA2 mutation (non-gBRCAm), maintenance olaparib was well tolerated, according to the secondary safety results from the phase IIIb OPINION study presented at SGO 2022.