BPaL regimen tied to liver injury
The overall risk of drug-induced liver injury (DILI) with the pretomanid, bedaquiline and linezolid (BPaL) regimen is lower compared with the isoniazid, rifampin, pyrazinamide and ethambutol (HRZE) regimen, a study has shown. However, the association between BPal and DILI remains significant, suggesting the need for careful monitoring during treatment.
