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Tricyclic antidepressant for IBS worth a try
15 Jan 2024
byJairia Dela Cruz
The tricyclic antidepressant amitriptyline, when used at low dose in the second-line treatment setting and titrated according to symptom response and side-effects, is safe and provides relief from symptoms of irritable bowel syndrome (IBS), as shown in the phase III ATLANTIS* trial.