News &amp; Updates

Exposure to nitroimidazole appears to mitigate the efficacy of nitroimidazole-based triple regimen, but not quadruple therapy, in patients with Helicobacter pylori infection, results of a study have shown.

Nitroimidazole exposure may dampen efficacy of triple therapy in H. pylori infection

Exercise capacity varies by sex in aortic stenosis patients

Exercise capacity and its determinants differ between men and women with aortic stenosis, a recent study has found.

Exercise capacity varies by sex in aortic stenosis patients

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

Post hoc results of the phase II FORWARD* study continued to reflect positive structural changes with the recombinant human fibroblast growth factor(FGF)-18 sprifermin, given the substantial dose-dependent increases in cartilage thickness gain and reductions in cartilage loss independent of location in the femorotibial joints (FTJ) of patients with knee osteoarthritis (OA).

Sprifermin keeps moving FORWARD in knee osteoarthritis treatment

Metformin potentially cardioprotective in nondiabetic adults

Treatment with metformin yields reductions in total and low-density lipoprotein cholesterol levels in individuals without diabetes, even providing an additional triglyceride-lowering effect among those with polycystic ovary syndrome (PCOS), according to the results of a meta-analysis.

Metformin potentially cardioprotective in nondiabetic adults

Protein mapping identifies compounds with potential antiviral activity against COVID-19

Nearly 70 compounds, including approved drugs and those still under clinical and preclinical investigation, may have potential activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), a new study has found.

Protein mapping identifies compounds with potential antiviral activity against COVID-19

Endoscopic surveillance for gastric cancer should continue long after H. pylori eradication

The risk of gastric cancer in patients cured of Helicobacter pylori appears to be greater in the second decade of follow-up than in the prior 10-year period, with the risk being specific to diffuse-type of disease among those with mild-to-moderate gastric atrophy, a study has reported.

Endoscopic surveillance for gastric cancer should continue long after H. pylori eradication

Inclisiran lowers LDL levels in patients at high risk for ASCVD

Treatment with inclisiran led to a significantly reduced low-density lipoprotein (LDL) cholesterol levels in patients with atherosclerotic cardiovascular disease (ASCVD), according to two phase III randomized clinical trials.

Inclisiran lowers LDL levels in patients at high risk for ASCVD

Educational interventions cut post-MI cardiovascular risk

Patient education programmes after myocardial infarction (MI) have long-lasting positive impacts on cardiovascular risk, a recent study has shown.

Educational interventions cut post-MI cardiovascular risk

Investigational HIV vaccine fails

24 Mar 2020 by

The National Institute of Allergy and Infectious Diseases (NIAID) recently made the decision to terminate the phase IIb/III HVTN 702 (Uhambo) trial that was investigating a vaccine to prevent HIV.

Investigational HIV vaccine fails

13 ways to fight COVID-19

COVID-19 is a novel disease, with no existing immunity. The virus can be transmitted from person to person, quickly and exponentially. Here’s what we can do to slow down the spread, if not contain the outbreak.

13 ways to fight COVID-19