News &amp; Updates

How long should high-risk patients undergoing PCI receive DAPT?

One-month treatment with dual antiplatelet therapy (DAPT) results in similar ischaemic outcomes and lower bleeding risk compared with 3 months of DAPT in patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI), a study has shown.

How long should high-risk patients undergoing PCI receive DAPT?

Beta-blocker withdrawal improves functional capacity in HFpEF

Withdrawal of beta-blocker treatment has led to increased maximal functional capacity in patients with heart failure with preserved ejection fraction (HFpEF) and chronotropic incompetence, reports a recent study, noting how use of beta-blockers deserved re-evaluation.

Beta-blocker withdrawal improves functional capacity in HFpEF

20 Nov 2021

AKI post-AMI tied to more serious kidney outcomes

19 Nov 2021 by

Patients who develop acute kidney injury (AKI) following an acute myocardial infarction (AMI) have an elevated risk of more serious kidney outcomes including persistent reductions in estimated glomerular filtration rate (eGFR), end-stage renal disease (ESRD), or renal death, according to results of the PARADISE-MI trial.

AKI post-AMI tied to more serious kidney outcomes

19 Nov 2021

Re-evaluate hs-cTnT cutoffs for MI type 5: study

Postoperative levels of high-sensitivity cardiac troponin T (hs-cTnT) often surpass defined cut-off values for myocardial infarction type 5 (MI-5; also known as peri-procedural MI), indicating the need to reassess current definitions, a recent study has found.

Re-evaluate hs-cTnT cutoffs for MI type 5: study

Moderate-intensity exercise improves muscle performance in statin users

A moderate-intensity endurance and resistance exercise training programme results in better muscle performance, capillarization, and mitochondrial content in both asymptomatic and symptomatic statin users without exacerbating muscle complaints, a study has shown. In addition, exercise training may even improve quality of life in symptomatic statin users.

Moderate-intensity exercise improves muscle performance in statin users

No trade-off between bleeding and ischaemic risk with abbreviated DAPT

19 Nov 2021 by

Stopping dual antiplatelet therapy (DAPT) after 1 month appeared safe in high-bleeding risk (HBR) patients with acute myocardial infarction (MI) who were implanted with a newer coronary stent, a prespecified subanalysis of the MASTER DAPT* trial has shown.

No trade-off between bleeding and ischaemic risk with abbreviated DAPT

19 Nov 2021

Bisoprolol insufficient to prevent perioperative myocardial injury during noncardiac surgery

Bisoprolol does not seem to exert a significant protective effect against perioperative myocardial injury in patients undergoing noncardiac surgery, a recent study has found.

Bisoprolol insufficient to prevent perioperative myocardial injury during noncardiac surgery

EMPEROR-Preserved: The first successful trial to improve outcomes in HFpEF

Heart failure with preserved ejection fraction (HFpEF) represents a significant unmet medical need. The EMPEROR-Preserved trial aimed to assess the impact of empagliflozin on cardiovascular outcomes in patients with HFpEF. On 27 August 2021, during the hotline session of the 2021 ESC Virtual Congress, the main results of the EMPEROR-Preserved trial were presented by Professor Stefan Anker, principal investigator of the study, and heart failure specialist at Charité Berlin, Germany.

EMPEROR-Preserved: The first successful trial to improve outcomes in HFpEF