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Seladelpar benefit in PBC sustained at 3 years

22 May 2025 by

The selective PPARδ* agonist seladelpar continues to demonstrate benefit in patients with primary biliary cholangitis (PBC) in the long-term pooled analysis from the ongoing open-label phase III ASSURE trial.

Seladelpar benefit in PBC sustained at 3 years

22 May 2025

Obesity ups risk of irritable bowel syndrome

21 May 2025

General and central obesity are both significant risk factors for the development of irritable bowel syndrome (IBS), suggests a study.

Obesity ups risk of irritable bowel syndrome

21 May 2025

Diet may influence CHF linked to gut microbiota

20 May 2025

An individual’s gut microbiota profile appears to be associated with chronic heart failure (CHF) risk factors, potentially mediated by microbial metabolites, results of a recent study have shown.

Diet may influence CHF linked to gut microbiota

20 May 2025

Higher alcohol withdrawal seen in acute pancreatitis patients living in vulnerable areas

20 May 2025

Patients with acute pancreatis who are residing in areas with higher Social Vulnerability Index (SVI) ranks are more likely to withdraw from alcohol use, according to a study.

Higher alcohol withdrawal seen in acute pancreatitis patients living in vulnerable areas

20 May 2025

Watch-and-wait approach feasible for therapy-responsive rectal cancer

19 May 2025

Survival outcomes do not differ between patients with locally advanced rectal cancer treated with mandatory total mesorectal excision (TME) and those on selective watch-and-wait (WW) strategies following total neoadjuvant therapy (TNT), reports a study.

Watch-and-wait approach feasible for therapy-responsive rectal cancer

19 May 2025

Linaclotide improves bowel symptoms in children with functional constipation

16 May 2025 by

Treatment with linaclotide led to significantly improved symptoms of incomplete bowel evacuation and straining in paediatric patients aged 6–17 years with functional constipation, according to a phase III study presented at DDW 2025.

Linaclotide improves bowel symptoms in children with functional constipation

16 May 2025

ACE-I/ARB use helps avert death in cirrhosis patients

13 May 2025

Exposure to angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARB) may prevent mortality among patients with cirrhosis, a study has shown.

ACE-I/ARB use helps avert death in cirrhosis patients

13 May 2025

TAF prophylaxis prevents mother-to-child transmission of HBV

13 May 2025

Treatment with tenofovir alafenamide (TAF) is generally safe and effective for the prevention of hepatitis B virus (HBV) mother-to-child transmission (MTCT), reports a study, noting that the expected 8-week prenatal duration is feasible.

TAF prophylaxis prevents mother-to-child transmission of HBV

13 May 2025

IBD patients who undergo coronary intervention at increased risk of MACE

08 May 2025

Patients with inflammatory bowel disease (IBD) have a higher likelihood of experiencing major adverse cardiovascular events (MACE) after coronary interventions, according to a study.

IBD patients who undergo coronary intervention at increased risk of MACE

08 May 2025

Which agents improve histology in EoE?

05 May 2025

Several medications such as orodispersible budesonide (ODB), oral viscous budesonide (OVB), and fluticasone, among others, demonstrate efficacy in the treatment of eosinophilic esophagitis (EoE) in adults and children, according to the results of a network meta-analysis.

Which agents improve histology in EoE?

05 May 2025

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Seladelpar benefit in PBC sustained at 3 years

Seladelpar benefit in PBC sustained at 3 years

Obesity ups risk of irritable bowel syndrome

Obesity ups risk of irritable bowel syndrome

Diet may influence CHF linked to gut microbiota

Diet may influence CHF linked to gut microbiota

Higher alcohol withdrawal seen in acute pancreatitis patients living in vulnerable areas

Higher alcohol withdrawal seen in acute pancreatitis patients living in vulnerable areas

Watch-and-wait approach feasible for therapy-responsive rectal cancer

Watch-and-wait approach feasible for therapy-responsive rectal cancer

Linaclotide improves bowel symptoms in children with functional constipation

Linaclotide improves bowel symptoms in children with functional constipation

ACE-I/ARB use helps avert death in cirrhosis patients

ACE-I/ARB use helps avert death in cirrhosis patients

TAF prophylaxis prevents mother-to-child transmission of HBV

TAF prophylaxis prevents mother-to-child transmission of HBV

IBD patients who undergo coronary intervention at increased risk of MACE

IBD patients who undergo coronary intervention at increased risk of MACE

Which agents improve histology in EoE?

Which agents improve histology in EoE?