News &amp; Updates

In this fourth issue, join us as we discover the unique biology Asians have with respect to diabetes. Take a closer look at trials evaluating whether empagliflozin’s cardiovascular and renal benefits – as analysed in Asians – are consistent with the overall trial population, and how it addresses unmet needs.

Empagliflozin near to us: Insights from its use in Asians

What genes are related to postmenopausal osteoporosis?

Biological signals involved in monocyte recruitment, monocyte/macrophage lineage development, osteoclast formation, and osteoclast differentiation may work together in peripheral blood monocytes (PBMs) that contribute to the pathogenesis of postmenopausal osteoporosis, reveals a study.

What genes are related to postmenopausal osteoporosis?

Left ventricular assist devices boost metabolic outcomes in diabetics

09 Jul 2020 by

Left ventricular assist devices (LVADs) trigger almost immediate favourable metabolic changes in both diabetics and nondiabetics, according to a recent study.

Left ventricular assist devices boost metabolic outcomes in diabetics

Nutrient diversion from proximal to distal small intestine eases hypotension in T2DM

Diversion of nutrients from the proximal to the distal small intestine may mitigate postprandial hypotension in patients with type 2 diabetes mellitus (T2DM), suggest the results of a recent study.

Nutrient diversion from proximal to distal small intestine eases hypotension in T2DM

Diabetes-related nutrition knowledge does not improve dietary adherence in T2DM patients

08 Jul 2020 by

Diabetes-related nutrition knowledge (DRNK) is not associated with adherence to dietary guidelines in patients with type 2 diabetes mellitus (T2DM), according to a Singapore study, noting multiple mediating factors when translating DRNK to practice.

Diabetes-related nutrition knowledge does not improve dietary adherence in T2DM patients

Autonomous cortisol secretion ups risk of atrial fibrillation

Patients with adrenal incidentalomas and autonomous cortisol secretion (ACS) appear to have a higher risk of atrial fibrillation (AF), a study has shown.

Autonomous cortisol secretion ups risk of atrial fibrillation

Early pregnancy PFAS exposure negatively tied to late pregnancy cortisone levels

An inverse association exists between early pregnancy maternal serum concentrations of perfluoroalkyl substances (S-PFAS) and late pregnancy diurnal urine (dU)-cortisone, which signifies a reduced activity of the enzyme 11β-hydroxysteroid dehydrogenase (11β-HSD) isoform 2, according to the results of a recent study.

Early pregnancy PFAS exposure negatively tied to late pregnancy cortisone levels

NTIS, hypothyroidism up risk of mortality, MACE in IHD patients

Nonthyroidal illness syndrome (NTIS) and hypothyroidism appear to increase the risk of all-cause mortality and major adverse cardiac events (MACE) in patients with ischaemic heart disease (IHD), suggests a recent study.

NTIS, hypothyroidism up risk of mortality, MACE in IHD patients

Dorzagliatin SEEDs good outcomes in T2D

07 Jul 2020 by

The novel dual-acting glucokinase activator (GKA) dorzagliatin provides good glycaemic control and has a favourable safety profile in Chinese patients with type 2 diabetes (T2D), the phase III SEED* study has shown.

Dorzagliatin SEEDs good outcomes in T2D