News & Updates

Serum vitamin D lower in melanoma patients

16 Mar 2021

Serum levels of vitamin D appear to be reduced among patients with melanoma and are associated with thicker melanomas and higher mitotic rates, a recent study has found.

Serum vitamin D lower in melanoma patients

16 Mar 2021

Metabolically unhealthy individuals at risk of pancreatic cancer

16 Mar 2021

Poor metabolic health appears to increase susceptibility to pancreatic cancer regardless of body mass index, a study suggests.

Metabolically unhealthy individuals at risk of pancreatic cancer

16 Mar 2021

Obesity worsens outcomes in all breast cancer subtypes

15 Mar 2021

Obesity appears to exert a negative effect on survival of women with breast cancer regardless of subtype, according to the results of a systematic review and meta-analysis.

Obesity worsens outcomes in all breast cancer subtypes

15 Mar 2021

Lenvatinib plus pembrolizumab improves PFS, OS and ORR in advanced clear-cell RCC

15 Mar 2021 by

Lenvatinib plus pembrolizumab significantly improves progression-free survival (PFS), overall survival (OS) and objective response rate (ORR) vs sunitinib in treatment-naïve patients with advanced clear-cell renal cell carcinoma (RCC), results of the phase III CLEAR study have shown.

Lenvatinib plus pembrolizumab improves PFS, OS and ORR in advanced clear-cell RCC

15 Mar 2021

Chemotherapy ups risk of 1-year hospitalization in TNBC

14 Mar 2021

Elderly patients with triple-negative breast cancer (TNBC) are more likely to undergo chemotherapy if they had been diagnosed at a more advanced stage, a recent study has found. In turn, receiving chemotherapy seems to aggravate their risk of being hospitalized within a year of diagnosis.

Chemotherapy ups risk of 1-year hospitalization in TNBC

14 Mar 2021

Hydrochlorothiazide use ups risk of in situ, invasive SCC, BCC

13 Mar 2021

High cumulative exposure to hydrochlorothiazide (HCTZ) may result in the development of keratinocyte carcinoma and invasive squamous cell carcinoma (SCC), a study has shown, noting that sun protective behaviours alone may not be enough to eliminate the carcinogenic potential of HCTZ.

Hydrochlorothiazide use ups risk of in situ, invasive SCC, BCC

13 Mar 2021

Metformin may prevent ER+ breast cancer

12 Mar 2021 by

Use of metformin in patients with type 2 diabetes (T2D) appears to reduce their risk of developing oestrogen receptor (ER)-positive breast cancer, especially with long-term use, although there is no change in overall breast cancer risk — suggesting that the protective benefit of metformin may vary by hormone receptor status, according to the Sister Study.

Metformin may prevent ER+ breast cancer

12 Mar 2021

Early-life secondhand smoke exposure implicated in ovarian cancer

12 Mar 2021

Children who live with parents who smoke are at risk of developing ovarian cancer, especially for nonserous or low-grade serous tumours, as adults, a study suggests.

Early-life secondhand smoke exposure implicated in ovarian cancer

12 Mar 2021

Genome analysis goes back in time to trace genesis of blood cancers

12 Mar 2021 by

Single point mutations that drive the development of myeloproliferative neoplasms (MPNs) can be traced back to decades before the diagnosis, according to a recent study. Such mutations also give the cells that harbour them a selective advantage.

Genome analysis goes back in time to trace genesis of blood cancers

12 Mar 2021

Extended follow-up of KEYNOTE-240 shows pembrolizumab maintains OS, PFS in advanced HCC

12 Mar 2021 by

Longer-term follow-up after the final analysis of the KEYNOTE-240* trial showed that improvements in overall survival (OS) and progression-free survival (PFS) with pembrolizumab were maintained in patients with advanced hepatocellular carcinoma (HCC) previously treated with sorafenib, according to updated results of the trial presented at ASCO GI 2021.

Extended follow-up of KEYNOTE-240 shows pembrolizumab maintains OS, PFS in advanced HCC

12 Mar 2021

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Serum vitamin D lower in melanoma patients

Serum vitamin D lower in melanoma patients

Metabolically unhealthy individuals at risk of pancreatic cancer

Metabolically unhealthy individuals at risk of pancreatic cancer

Obesity worsens outcomes in all breast cancer subtypes

Obesity worsens outcomes in all breast cancer subtypes

Lenvatinib plus pembrolizumab improves PFS, OS and ORR in advanced clear-cell RCC

Lenvatinib plus pembrolizumab improves PFS, OS and ORR in advanced clear-cell RCC

Chemotherapy ups risk of 1-year hospitalization in TNBC

Chemotherapy ups risk of 1-year hospitalization in TNBC

Hydrochlorothiazide use ups risk of in situ, invasive SCC, BCC

Hydrochlorothiazide use ups risk of in situ, invasive SCC, BCC

Metformin may prevent ER+ breast cancer

Metformin may prevent ER+ breast cancer

Early-life secondhand smoke exposure implicated in ovarian cancer

Early-life secondhand smoke exposure implicated in ovarian cancer

Genome analysis goes back in time to trace genesis of blood cancers

Genome analysis goes back in time to trace genesis of blood cancers

Extended follow-up of KEYNOTE-240 shows pembrolizumab maintains OS, PFS in advanced HCC

Extended follow-up of KEYNOTE-240 shows pembrolizumab maintains OS, PFS in advanced HCC