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Datopotamab deruxtecan improves survival in breast cancer patients not eligible for immunotherapy

06 Nov 2025 by

First-line treatment with datopotamab deruxtecan (Dato-DXd) results in statistically significant and clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) compared with chemotherapy in patients with locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), as shown by the results of the phase III TROPION-Breast02 trial.

Datopotamab deruxtecan improves survival in breast cancer patients not eligible for immunotherapy

06 Nov 2025

Anti-synthetase syndrome linked to cancer-related myositis

06 Nov 2025

Patients with anti-synthetase syndrome show a higher incidence of cancer-related myositis than the general population, suggests a study.

Anti-synthetase syndrome linked to cancer-related myositis

06 Nov 2025

High BMI tied to ulnar nerve entrapment development in nondiabetic individuals

06 Nov 2025 by

A longitudinal study from Sweden shows an association between high BMI and the development of ulnar nerve entrapment (UNE) in a middle-aged cohort of individuals without diabetes from northern Europe, with over 25 years of follow-up.

High BMI tied to ulnar nerve entrapment development in nondiabetic individuals

06 Nov 2025

Early surgery linked to better long-term outcomes in asymptomatic severe mitral regurgitation

06 Nov 2025

Timing of surgery appears to influence long-term outcomes in asymptomatic severe mitral regurgitation, such that performing the surgery early leads to better results over the long term than waiting until symptoms develop, according to a study.

Early surgery linked to better long-term outcomes in asymptomatic severe mitral regurgitation

06 Nov 2025

Pilates may be beneficial in knee OA rehabilitation

05 Nov 2025

In patients with knee osteoarthritis who are undergoing rehabilitation, Pilates helps alleviate pain and yields improvements in range of motion, proprioception, dynamic balance, and quality of life, according to a systematic review and meta-analysis.

Pilates may be beneficial in knee OA rehabilitation

05 Nov 2025

FIT kit-dispensing kiosk to promote uptake of CRC screening in SG

05 Nov 2025 by

An automated kiosk that dispenses faecal immunochemical test (FIT) kits, called the KIPFIT*, has the potential to increase colorectal (CRC) screening uptake in Singapore, as shown in a study.

FIT kit-dispensing kiosk to promote uptake of CRC screening in SG

05 Nov 2025

Long-term DAPT reduces risk of cardiac death, myocardial infarction

05 Nov 2025

Prolonged dual antiplatelet therapy (DAPT) duration appears to lower the risk of cardiac death and myocardial infarction, but may increase the risk of minor bleeding, in patients undergoing chronic total occlusion percutaneous coronary intervention, reports a recent study.

Long-term DAPT reduces risk of cardiac death, myocardial infarction

05 Nov 2025

Amivantamab-lazertinib combo improves survival by reducing resistance mechanisms in NSCLC

05 Nov 2025 by

An updated analysis of MARIPOSA reveals significant reductions in the incidence of MET and EGFR resistance alterations with first-line amivantamab plus lazertinib compared with osimertinib, with no upregulation in other resistance pathways, in patients with nonsmall cell lung cancer (NSCLC).

Amivantamab-lazertinib combo improves survival by reducing resistance mechanisms in NSCLC

05 Nov 2025

Tislelizumab outclasses docetaxel in advanced/metastatic NSCLC

05 Nov 2025 by

Treatment with tislelizumab results in longer overall survival (OS), prolonged progression-free survival (PFS), higher objective response rates (ORRs), more durable responses, and fewer grade ≥3 treatment-emergent (TEAEs) and treatment-related adverse events (TRAEs) compared with docetaxel, according to the RATIONALE-303 study.

Tislelizumab outclasses docetaxel in advanced/metastatic NSCLC

05 Nov 2025

Endometriosis risk reduced with modest intake of soy products

05 Nov 2025

New research suggests that incorporating even modest amounts of soy into the diet may provide a protective benefit against endometriosis in women.

Endometriosis risk reduced with modest intake of soy products

05 Nov 2025

News & Updates

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Datopotamab deruxtecan improves survival in breast cancer patients not eligible for immunotherapy

Datopotamab deruxtecan improves survival in breast cancer patients not eligible for immunotherapy

Anti-synthetase syndrome linked to cancer-related myositis

Anti-synthetase syndrome linked to cancer-related myositis

High BMI tied to ulnar nerve entrapment development in nondiabetic individuals

High BMI tied to ulnar nerve entrapment development in nondiabetic individuals

Early surgery linked to better long-term outcomes in asymptomatic severe mitral regurgitation

Early surgery linked to better long-term outcomes in asymptomatic severe mitral regurgitation

Pilates may be beneficial in knee OA rehabilitation

Pilates may be beneficial in knee OA rehabilitation

FIT kit-dispensing kiosk to promote uptake of CRC screening in SG

FIT kit-dispensing kiosk to promote uptake of CRC screening in SG

Long-term DAPT reduces risk of cardiac death, myocardial infarction

Long-term DAPT reduces risk of cardiac death, myocardial infarction

Amivantamab-lazertinib combo improves survival by reducing resistance mechanisms in NSCLC

Amivantamab-lazertinib combo improves survival by reducing resistance mechanisms in NSCLC

Tislelizumab outclasses docetaxel in advanced/metastatic NSCLC

Tislelizumab outclasses docetaxel in advanced/metastatic NSCLC

Endometriosis risk reduced with modest intake of soy products

Endometriosis risk reduced with modest intake of soy products