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High-intensity statins help lower cholesterol among diabetics
Treatment with rosuvastatin, given at moderate and high intensity doses, as well as simvastatin and atorvastatin, given at high intensity doses, modestly reduce levels of nonhigh-density lipoprotein cholesterol (non-HDL-C) in diabetic patients over 12 weeks compared with placebo, a study has shown.
High-intensity statins help lower cholesterol among diabetics
05 Apr 2022ED patients who do not respond to PDE5I may benefit from topical alprostadil–PDE5i combo
For men with erectile dysfunction (ED) who show a lack of response to oral phosphodiesterase type 5 inhibitors (PDE5Is), combination therapy with topical alprostadil plus PDE5Is seems favourable, producing greater improvements in sexual function without compromising safety compared with topical alprostadil alone, as shown in a study.
ED patients who do not respond to PDE5I may benefit from topical alprostadil–PDE5i combo
04 Apr 2022Topical therapy plus microneedling safe, effective in melasma management
Use of microneedling appears to be a beneficial adjunct to topical medications in the treatment of melasma, suggests a recent study.
Topical therapy plus microneedling safe, effective in melasma management
03 Apr 2022Tislelizumab produces long-term benefits in relapsed, refractory classical Hodgkin lymphoma
Treatment with the antiprogrammed cell death protein 1 (anti–PD-1) monoclonal antibody tislelizumab yields high response rates in relapsed or refractory classical Hodgkin's lymphoma, with a similar toxicity profile as other anti–PD-1 therapies, as shown in the extended results of a phase II trial.
Tislelizumab produces long-term benefits in relapsed, refractory classical Hodgkin lymphoma
01 Apr 2022Empagliflozin benefits similar between MRA users, nonusers
In patients with heart failure (HF) and preserved ejection fraction, treatment with empagliflozin delivers comparable benefits in reducing first hospitalization for HF or cardiovascular death (primary outcome) between users and nonusers of mineralocorticoid receptor antagonists (MRA), reports a study.