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5-ASA use in paediatric CD common, deviates from recommended practices
Children with Crohn’s disease (CD) are often treated with 5-aminosalicylate (5-ASA) contrary to guidelines, and this practice is associated with a substantial delay in initiating biologic therapy, according to a study presented at this year’s Crohn's & Colitis Congress.
5-ASA use in paediatric CD common, deviates from recommended practices
07 Feb 2023DAPT with cilostazol reduces stroke recurrence without raising bleeding risk
Dual antiplatelet therapy (DAPT) using cilostazol appears to be more beneficial than single antiplatelet therapy, with the results of a study suggesting that DAPT helps lower the incidence of ischemic stroke recurrence without increasing the risk of severe or life-threatening bleeding.
DAPT with cilostazol reduces stroke recurrence without raising bleeding risk
07 Feb 2023Mutational ctDNA analysis helps predict benefit of 2L ripretinib or sunitinib in GIST
Next-generation sequencing (NGS)–based analysis of circulating tumour DNA (ctDNA) helps predict benefit of second-line (2L) ripretinib or sunitinib therapy in patients with imatinib-resistant advanced gastrointestinal stromal tumours (GIST), an exploratory subanalysis of the INTRIGUE trial has shown.
Mutational ctDNA analysis helps predict benefit of 2L ripretinib or sunitinib in GIST
07 Feb 2023Does LMWH improve live birth rate in women with inherited thrombophilia and miscarriage history?
The use of low-molecular-weight heparin (LMWH) during pregnancy did not increase the likelihood of live birth compared with standard surveillance in women with inherited thrombophilia who have experienced multiple miscarriages, according to a multinational study presented at ASH 2022.
Does LMWH improve live birth rate in women with inherited thrombophilia and miscarriage history?
06 Feb 2023Radiation therapy may raise colorectal cancer risk among Hodgkin's lymphoma survivors
Individuals who received radiation therapy for Hodgkin's lymphoma are at increased risk of colorectal cancer, as reported in a study.
Radiation therapy may raise colorectal cancer risk among Hodgkin's lymphoma survivors
06 Feb 2023Isolated anti-HBc positivity ups liver-related death risk
Isolated hepatitis B core antibody (anti-HBc) positivity appears to increase the risk of liver-related and liver cancer mortality, particularly when accompanied by a high fibrosis score, according to a study of Korean adults.
Isolated anti-HBc positivity ups liver-related death risk
06 Feb 2023Pharmacist-led collaborative gout clinic helps patients achieve serum uric acid goals
A collaborative clinic led by a pharmacist helps patients with gout to attain better clinical outcomes in the management of their condition, even in the presence of renal impairment, reports a Singapore study. The clinic provides safe, stepwise increments of urate-lowering therapy (ULT) in addition to serum uric acid (SUA) monitoring and adherence reinforcement through frequent initial visits.