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Etanercept biosimilar demonstrates long-term safety, efficacy in rheumatoid arthritis
YLB113, a biosimilar of the reference product etanercept, appears to be safe for long-term treatment of patients with rheumatoid arthritis, with efficacy sustained for up to 96 weeks, according to a study. Notably, the biosimilar is associated with fewer cases of injection-site reactions and injection-site erythema compared with the reference.
Etanercept biosimilar demonstrates long-term safety, efficacy in rheumatoid arthritis
14 Jan 2023Ritlecitinib, brepocitinib superior to placebo for inducing remission in UC
Ritlecitinib and brepocitinib as induction therapies for ulcerative colitis (UC) appear to be more effective than placebo while having an acceptable short-term safety profile, according to the results of a phase IIb study.
Ritlecitinib, brepocitinib superior to placebo for inducing remission in UC
13 Jan 2023Regular coffee intake may lower T2D risk in women with gestational diabetes
Women with a history of gestational diabetes mellitus (GDM) may benefit from habitual consumption of caffeinated coffee to prevent progression to type 2 diabetes (T2D) and have a more favourable metabolic profile, suggests a study.
Regular coffee intake may lower T2D risk in women with gestational diabetes
13 Jan 2023Regdanvimab for COVID-19 effective against Delta variant
The neutralizing antibody regdanvimab appears to be useful in the treatment of mild-to-moderate COVID-19, with a recent study showing that the drug may prevent disease worsening in patients, including those infected with the Delta variant.
Regdanvimab for COVID-19 effective against Delta variant
13 Jan 2023KRAS G12C inhibitors show promise in metastatic colorectal and pancreatic cancers
The KRASG12C inhibitors, adagrasib and sotorasib, have shown promising antitumour activity in patients with heavily pretreated metastatic colorectal cancer (mCRC) and metastatic pancreatic cancer, respectively.