News & Updates

Antibiotics improve disease activity in adults with Crohn’s disease

26 Jan 2021 by

A meta-analysis presented at Crohn’s and Colitis 2021 demonstrated reductions in disease activity among adults with Crohn’s disease (CD) who were taking antibiotics.

Antibiotics improve disease activity in adults with Crohn’s disease

26 Jan 2021

Subcutaneous vedolizumab maintenance attains clinical remission in ulcerative colitis

26 Jan 2021 by

Patients with ulcerative colitis (UC) who received a subcutaneous (SC) formulation of vedolizumab as maintenance therapy achieved clinical remission at 52 weeks, according to the VISIBLE 1* trial presented at AIBD 2020.

Subcutaneous vedolizumab maintenance attains clinical remission in ulcerative colitis

26 Jan 2021

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

25 Jan 2021 by

The addition of chemotherapy to endocrine therapy improved invasive disease-free survival (IDFS) in premenopausal women with lymph node-positive early stage hormone receptor-positive (HR+) HER2-negative (HER2-) breast cancer with recurrence score ≤25, according to early results of the phase III SWOG S1007 RxPonder* trial presented at SABCS 2020. However, the benefits did not appear to extend to postmenopausal women.

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

25 Jan 2021

Meta-analysis: Age is just a number with regard to lipid-lowering therapy

25 Jan 2021 by

The oldest patients get as much cardioprotective benefit from reducing low-density lipoprotein (LDL) cholesterol levels as younger patients, according to a study, suggesting that age should pose no barrier to the use of lipid-lowering treatments.

Meta-analysis: Age is just a number with regard to lipid-lowering therapy

25 Jan 2021

Oral sodium bicarbonate a feasible alternative for high-dose MTX urine alkalinization

25 Jan 2021

Oral sodium bicarbonate with Lactated Ringer’s solution (LR) is a good option for urine alkalization to ease nephrotoxicity caused by high-dose methotrexate (MTX; doses ≥500 mg/m2), suggests a study. Moreover, the total dose of sodium bicarbonate used is lower in the oral than the intravenous (IV) cohort, with no additional delays in clearance.

Oral sodium bicarbonate a feasible alternative for high-dose MTX urine alkalinization

25 Jan 2021

Hydrocortisone does not affect time to shock reversal in cancer patients with septic shock

25 Jan 2021

Use of hydrocortisone relative to methylprednisolone appears to have no impact on time to shock reversal in cancer patients with septic shock, results of a study have shown.

Hydrocortisone does not affect time to shock reversal in cancer patients with septic shock

25 Jan 2021

Sotagliflozin SCORED favourably in patients with T2D, CKD

25 Jan 2021 by

Use of the sodium-glucose cotransporter 2 (SGLT2) inhibitor sotagliflozin led to a reduction in the risk of deaths from cardiovascular (CV) causes, hospitalizations for heart failure (HF), and urgent visits for HF compared with placebo among patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) regardless of the degree of albuminuria, the SCORED* trial has shown.

Sotagliflozin SCORED favourably in patients with T2D, CKD

25 Jan 2021

Oestrogen receptor beta compounds do little in perimenopause-related depression

25 Jan 2021

Oestradiol, raloxifene, and the proprietary phytoestrogen compound rimostil appear to convey no therapeutic benefits in perimenopause-related depression (PMD), as shown in a study. However, oestradiol has the potential to improve depression ratings than rimostil.

Oestrogen receptor beta compounds do little in perimenopause-related depression

25 Jan 2021

Temozolomide a good option for late adjuvant therapy in melanoma patients

24 Jan 2021

Use of a single-agent temozolomide appears to be an effective alternative to late adjuvant therapy in patients with melanoma if novel treatments, such as targeting and immune therapies, are not available, suggests a recent study.

Temozolomide a good option for late adjuvant therapy in melanoma patients

24 Jan 2021

≥50% of COVID-19 cases may be due to asymptomatic transmission

23 Jan 2021 by

SARS-CoV-2 transmission from asymptomatic individuals could account for more than half of all transmissions, according to estimates from a modelling study and data from a real-world study —suggesting that isolation of symptomatic cases alone is insufficient for controlling the ongoing spread of SARS-CoV-2.

≥50% of COVID-19 cases may be due to asymptomatic transmission

23 Jan 2021

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Antibiotics improve disease activity in adults with Crohn’s disease

Antibiotics improve disease activity in adults with Crohn’s disease

Subcutaneous vedolizumab maintenance attains clinical remission in ulcerative colitis

Subcutaneous vedolizumab maintenance attains clinical remission in ulcerative colitis

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

Adding chemo to endocrine therapy may benefit premenopausal women with early breast cancer

Meta-analysis: Age is just a number with regard to lipid-lowering therapy

Meta-analysis: Age is just a number with regard to lipid-lowering therapy

Oral sodium bicarbonate a feasible alternative for high-dose MTX urine alkalinization

Oral sodium bicarbonate a feasible alternative for high-dose MTX urine alkalinization

Hydrocortisone does not affect time to shock reversal in cancer patients with septic shock

Hydrocortisone does not affect time to shock reversal in cancer patients with septic shock

Sotagliflozin SCORED favourably in patients with T2D, CKD

Sotagliflozin SCORED favourably in patients with T2D, CKD

Oestrogen receptor beta compounds do little in perimenopause-related depression

Oestrogen receptor beta compounds do little in perimenopause-related depression

Temozolomide a good option for late adjuvant therapy in melanoma patients

Temozolomide a good option for late adjuvant therapy in melanoma patients

≥50% of COVID-19 cases may be due to asymptomatic transmission

≥50% of COVID-19 cases may be due to asymptomatic transmission