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Prexasertib works in select patients with recurrent ovarian cancer
CHK1 inhibition with prexasertib appears to have durable activity in some patients with recurrent ovarian cancer regardless of clinical characteristics, BRCA status, or prior therapies, according to the results of a phase II trial.
Prexasertib works in select patients with recurrent ovarian cancer
14 Oct 2022
Sacituzumab govitecan confers OS benefit for HR+/HER2– metastatic breast cancer
In the second interim overall survival (OS) analysis of the phase III TROPiCS-02 study, sacituzumab govitecan (SG) – a first-in-class Trop-2*-directed antibody-drug conjugate approved for triple-negative metastatic breast cancer (mBC) with ≥2 prior therapies (≥1 in the metastatic setting) – conferred an OS benefit for pretreated HR+/HER2– mBC, compared with treatment of physician’s choice (TPC**).
Sacituzumab govitecan confers OS benefit for HR+/HER2– metastatic breast cancer
12 Oct 2022
Boys born to moms with GDM at risk of neurodevelopmental delays
Neurodevelopment appears to be significantly delayed at up to 4 years of age in boys who are born to mothers with gestational diabetes mellitus (GDM), reports a recent study.
Boys born to moms with GDM at risk of neurodevelopmental delays
10 Oct 2022
Trans fatty acid intake tied to hypertensive disorders of pregnancy
Prepregnancy intakes of total fat, unsaturated fat, and monounsaturated fatty acid (MUFA) do not appear to contribute to hypertensive disorders of pregnancy (HDP), but trans fatty acid (TFA) shows a positive association with HDP, reports a study.