News &amp; Updates

In neonates who have asymptomatic hypoglycaemia in the first 48 hours of life, administering dextrose gel is useful and minimizes requirement for intravenous fluids, as shown in a study.

Dextrose gel reduces need for intravenous fluids in babies with asymptomatic hypoglycaemia

Newborn screening facilitates timely detection, treatment of late-onset Pompe disease

In one-fifth of patients, late-onset Pompe disease (LOPD) manifests within 15 years of detection, a recent study has found. Newborn screening (NBS) can help detect LOPD early despite having no symptoms, and may lead to timely treatment administration.

Newborn screening facilitates timely detection, treatment of late-onset Pompe disease

Loneliness tied to pain-fatigue-depression cluster in older adults

High levels of loneliness among elderly adults increase the likelihood of reporting pain, fatigue, depression, and the cluster of all three symptoms, reports a recent study.

Loneliness tied to pain-fatigue-depression cluster in older adults

Fewer hospitalizations with omicron vs delta suggest reduced severity of omicron variant

Infection with the omicron variant of SARS-CoV-2 was less likely to result in hospitalization than infection with the delta variant, according to an observational study from Denmark presented at ECCMID 2022 and published in The Lancet.

Fewer hospitalizations with omicron vs delta suggest reduced severity of omicron variant

23 May 2022

‘1-2-3-4-day rule’: Initiating DOACs according to stroke severity may be the way to go

Following nonvalvular atrial fibrillation (NVAF)-associated stroke events, a graded increase in delay in direct oral anticoagulants (DOACs) initiation of between 1 and 4 days, depending on the severity of the index event, appears to be effective for recurrent stroke prevention and does not compromise safety both in Asians and Europeans, according to a recent study.

‘1-2-3-4-day rule’: Initiating DOACs according to stroke severity may be the way to go

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

Poor outcomes are not significantly different in between patients with high-risk cutaneous squamous cell carcinomas treated with margin-negative resection only and those who underwent surgery with adjuvant radiotherapy, reveals a study.

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

Intensive BP management reduces CVD deaths in overweight, obese patients

Intensive management of blood pressure (BP) leads to a significant reduction in cardiovascular events in overweight, obese I, and obese II patients without elevating safety risks, a study has shown.

Intensive BP management reduces CVD deaths in overweight, obese patients

23 May 2022

Steroid plus anti-TNF-α proven effective in SJS/TEN

The addition of antitumour necrosis factor-alpha (anti-TNF-α) to steroid treatment may help improve outcomes for patients with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), suggest the results of a recent study.

Steroid plus anti-TNF-α proven effective in SJS/TEN

Upadacitinib provides robust, long-term control of moderate-to-severe AD

Follow-up data from two replicate ongoing phase III trials – Measure Up 1 and Measure Up 2 – demonstrated favourable longer-term benefit-risk profile of upadacitinib in adolescents and adults with moderate-to-severe atopic dermatitis (AD).

Upadacitinib provides robust, long-term control of moderate-to-severe AD

23 May 2022

Different booster shot strengthens immune response against Omicron