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IM noninferior to IV sotrovimab for COVID-19
In high-risk nonhospitalized patients with mild-to-moderate COVID-19, intramuscular administration of the monoclonal antibody sotrovimab was noninferior to IV infusion of the drug, according to findings from the phase III COMET-TAIL trial presented at CROI 2022.
IM noninferior to IV sotrovimab for COVID-19
17 Feb 2022
COVID-19 infection relatively rare in vaccinated IBD patients
Patients with inflammatory bowel disease (IBD) who have completed a COVID-19 vaccine regimen have a low risk of developing COVID-19, though receipt of mRNA vaccines may offer better protection, according to a small study presented at the Crohn’s and Colitis Congress 2022.
COVID-19 infection relatively rare in vaccinated IBD patients
15 Feb 2022
Extensive influenza testing needed in pneumonia patients
Most patients with community-acquired pneumonia go untested for influenza even during flu season, which is unfortunate since a positive test result facilitates antiviral therapy, and early treatment leads to lower mortality, according to a study.
Extensive influenza testing needed in pneumonia patients
10 Feb 2022
Casirivimab-imdevimab combo prevents progression from asymptomatic to symptomatic COVID-19
Treatment with the combination therapy of casirivimab and imdevimab prevents the risk of developing symptomatic COVID-19 among asymptomatic individuals with SARS-CoV-2 infection in a household close-contact setting, according to a recent study.
Casirivimab-imdevimab combo prevents progression from asymptomatic to symptomatic COVID-19
10 Feb 2022
CPAP reduces tracheal intubation, mortality in adults with COVID-19–related acute hypoxemic respiratory failure
The use of continuous positive airway pressure (CPAP) significantly reduces the risk of tracheal intubation and mortality among hospitalized patients with COVID-19–related acute hypoxemic respiratory failure, according to the RECOVERY-RS* trial.
CPAP reduces tracheal intubation, mortality in adults with COVID-19–related acute hypoxemic respiratory failure
08 Feb 2022
Fungal infections common in COVID-19 patients who require mechanical ventilation
Patients with COVID-19 who received mechanical ventilation while admitted to the intensive care unit (ICU) have an elevated risk of invasive fungal infections (IFIs), according to results of the MYCOVID study from France. Furthermore, patients with COVID-19–associated pulmonary aspergillosis (CAPA) may be at an increased risk for death.
