News &amp; Updates

Medications that regulate low‐density lipoprotein‐cholesterol (LDL‐C) levels appear to contribute to a slight increase in the risk of haemorrhagic stroke events, according to a meta-analysis.

LDL-C–lowering therapies bear a small risk of haemorrhagic stroke

Pembrolizumab delivers long-term survival benefits in advanced esophageal cancer

First-line pembrolizumab (pembro) plus chemotherapy (chemo) in patients with untreated advanced esophageal cancer demonstrates robust efficacy after 5 years, with no new safety concerns, when compared with placebo plus chemo, according to a study presented at ASCO GI 2024.

Pembrolizumab delivers long-term survival benefits in advanced esophageal cancer

Methylnaltrexone proves safety in paediatric oncology patients with constipation

Subcutaneous methylnaltrexone is safe to use in children with cancer who have opioid-induced constipation, suggest the results of a study. In addition, this agent stimulates bowel movements in more than a third of paediatric patients.

Methylnaltrexone proves safety in paediatric oncology patients with constipation

24 Feb 2024

$Eye diseases spell increased risk of falls, fractures$

Eye diseases spell increased risk of falls, fractures

People with cataract, age-related macular degeneration (AMD), and/or glaucoma are at heightened risk of both falls or fractures, as shown in a study.

Eye diseases spell increased risk of falls, fractures

Abatacept may mitigate rheumatoid arthritis development in at-risk individuals

The use of abatacept in adults at high risk of rheumatoid arthritis helps protect against disease onset, as shown in the phase IIB APIPPRA study.

Abatacept may mitigate rheumatoid arthritis development in at-risk individuals

24 Feb 2024

Severe OSA in IHD patients ups AF risk during sleep

Severe obstructive sleep apnoea (OSA) in patients with ischaemic heart disease (IHD) is associated with an increased risk of atrial fibrillation (AF) during sleep, according to a Singapore study.

Severe OSA in IHD patients ups AF risk during sleep

Does hand grip strength correlate with clinical disease activity in CD?

23 Feb 2024 by

Hand grip may be associated with clinical disease activity in patients with Crohn’s disease (CD), but hand grip measurements alone may not be the best predictor of disease activity or related disability, suggests a study presented at Crohn’s and Colitis Congress 2024.

Does hand grip strength correlate with clinical disease activity in CD?

Patients on anticancer therapeutic agents may develop carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is not uncommon in patients being treated with anticancer therapeutic agents, reports a study. Electrodiagnostic (EDX) studies and ultrasound (US) are necessary in the diagnostic assessment of these individuals.

Patients on anticancer therapeutic agents may develop carpal tunnel syndrome

Thoracoscopic esophagectomy better than open surgery in esophageal cancer

23 Feb 2024 by

Thoracoscopic esophagectomy (TE) has demonstrated its noninferiority to open transthoracic esophagectomy (OE) for patients with thoracic esophageal cancer in a study presented at ASCO GI 2024.

Thoracoscopic esophagectomy better than open surgery in esophageal cancer

Serum klotho reduction ups death risk in persons with vitamin D deficiency

A decreasing klotho, a biomarker of vitamin D activation and metabolism, plays a key role in the association between 25-hydroxyvitamin D (25[OH]D) and mortality, reveals a study. This finding suggests that a disruption in vitamin D metabolism leads to an increased risk of death.

Serum klotho reduction ups death risk in persons with vitamin D deficiency