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Tryptophan, IPA levels tied to lower mortality in coronary artery disease

02 Nov 2022

Levels of indole-3-propionic acid (IPA), a microbiota-produced tryptophan metabolite, and plasma tryptophan appear to contribute to a reduced risk of cardiovascular and all-cause mortality in patients with coronary artery disease (CAD), reveals a prospective study.

02 Nov 2022

TNF inhibition beyond 24 weeks: How safe in pregnant mums?

02 Nov 2022 by

Continued treatment with tumor necrosis factor (TNF) inhibitors after 24 weeks of pregnancy appears safe and is associated with lower chances of maternal inflammatory bowel disease (IBD) relapse, without increasing adverse neonatal outcomes, new research suggests.

02 Nov 2022

Original New Drug Application Approvals by US FDA (16 - 31 October 2022)

02 Nov 2022

New drug applications approved by US FDA as of 16 - 31 October 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

02 Nov 2022

Low-carb diet lowers glucose in absence of medication

02 Nov 2022

A low-carbohydrate dietary intervention helps with glucose control in individuals with elevated HbA1c but not taking glucose-lowering medications, as shown in a study.

02 Nov 2022

Does having a pet in early childhood reduce the risk of mental illness in adolescence?

02 Nov 2022 by

Having a pet dog or cat during early childhood is associated with a reduced risk of mental illnesses in adolescence, a retrospective cohort study in the US has shown.

02 Nov 2022

RNA nanoparticle as novel agent for atherosclerosis treatment

02 Nov 2022 by

Researchers from the Chinese University of Hong Kong (CUHK) have developed a novel RNA nanoparticle that can target and treat atherosclerotic plaques without inducing severe toxicity, paving the way for the use of RNA nanotechnology in cardiovascular disease (CVD) management.

02 Nov 2022