News & Updates

Triplet therapy combining androgen deprivation therapy (ADT), docetaxel, and abiraterone-prednisone improves overall survival (OS) in men with de novo metastatic castration-sensitive prostate cancer (mCSPC), according to results of the phase III PEACE-1 trial presented at ESMO 2021.

The prevalence of erectile dysfunction is significantly higher among men participating in in vitro fertilization (IVF) in order to conceive compared to couples who conceived spontaneously, reveals a recent study. Such occurrence leads to a very high rate of phosphodiesterase-5 inhibitor use.

Certain systemic diseases, such as Sjögren syndrome (SS), facial rosacea, rheumatoid arthritis (RA), and peripheral artery disease, and a history of daily cigarette smoking are significantly associated with more severe dry eye disease (DED) signs, a study has found.

Acid suppression (AS) medications, such as proton pump inhibitors (PPIs) and histamine type-2 receptor antagonists (H2RAs), weaken the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) in nonsmall cell lung cancer (NSCLC), resulting in worse survival outcomes, according to a recent Singapore meta-analysis.

Treatment with the novel, selective peroxisome proliferator-activated receptor α modulator (SPPARMα) pemafibrate appears to produce a significant reduction in liver stiffness but not in liver fat content in patients with high-risk nonalcoholic fatty liver disease (NAFLD), according to the results of a phase II trial.

In patients with acute coronary syndrome (ACS) or stable angina pectoris (SAP), undergoing noncardiac surgery after stenting increases the risk of myocardial infarction (MI), but only when procedures are performed during acute admission, a recent study has found.