News & Updates

Idiopathic Parkinson’s disease: Which dopamine agonist is associated with lower risk of impulse control–related behavioural disorders?

06 Feb 2024 by

In Chinese patients with idiopathic Parkinson’s disease (IPD) on their first dopamine agonist (DA) monotherapy for >6 months, bromocriptine is associated with a lower risk of impulse control–related behavioural disorders (ICRDs) compared with pramipexole and ropinirole, an observational cohort study in Hong Kong has shown. Rotigotine demonstrated a trend towards lower ICRD risk than the latter two DAs.

Idiopathic Parkinson’s disease: Which dopamine agonist is associated with lower risk of impulse control–related behavioural disorders?

06 Feb 2024

Comorbid sleep-disordered breathing and AF poststroke linked to elevated mortality, recurrence

04 Feb 2024

Stroke patients with comorbid moderate-to-severe sleep-disordered breathing (SDB) and atrial fibrillation (AF) are at heightened risk of long-term mortality or recurrent cerebro-cardiovascular events, according to a study.

Comorbid sleep-disordered breathing and AF poststroke linked to elevated mortality, recurrence

04 Feb 2024

Oxathridine linked to pseudohallucinations

01 Feb 2024

Administration of oxathridine, a first-in-class histamine-3 receptor partial agonist, results in some serious adverse events (AEs), including orthostatic hypotension and pseudohallucinations in healthy male volunteers, results of a study have shown.

Oxathridine linked to pseudohallucinations

01 Feb 2024

Physical activity boosts mental health in young people with neurodevelopmental disorders

01 Feb 2024

In children and adolescents with different types of neurodevelopmental disorders, physical activity interventions exert beneficial effects on mental health, including cognitive function, psychological well-being, internalizing, and externalizing problems, according to the results of a meta-analysis.

Physical activity boosts mental health in young people with neurodevelopmental disorders

01 Feb 2024

Acupuncture shows promise for poststroke motor aphasia

30 Jan 2024 by

When combined with language training and conventional treatment, a 6-week course of acupuncture helps improve outcomes, including language function, in stroke survivors with motor aphasia, as shown in a study.

Acupuncture shows promise for poststroke motor aphasia

30 Jan 2024

Intracranial sinusitis complications may cause serious injury in children

25 Jan 2024

Intracranial pyogenic complications of sinusitis remain a serious concern among children, potentially leading to severe morbidity, results of a 20-year study have shown.

Intracranial sinusitis complications may cause serious injury in children

25 Jan 2024

Bacterial meningitis in childhood linked to long-term disabilities

25 Jan 2024

Individuals who contracted bacterial meningitis as children appear to be at greater risk of having long-term disabilities, as reported in a study from Sweden.

Bacterial meningitis in childhood linked to long-term disabilities

25 Jan 2024

Adding bevacizumab to chemo enhances antitumour activity in children with R/R neuroblastoma

23 Jan 2024 by

Adding bevacizumab (B) to temozolomide (T)-based chemotherapy increases overall response rate (ORR) in children with relapsed/refractory (R/R) neuroblastoma, according to results of the three-by-two factorial, randomized controlled phase II BEACON-Neuroblastoma trial.

Adding bevacizumab to chemo enhances antitumour activity in children with R/R neuroblastoma

23 Jan 2024

Levetiracetam use during pregnancy poses no significant risks of birth defects, miscarriage

22 Jan 2024 by

Expectant mothers who use the antiseizure medication levetiracetam as monotherapy do not appear to have increased overall risk of major birth defects or miscarriage, as reported in a study.

Levetiracetam use during pregnancy poses no significant risks of birth defects, miscarriage

22 Jan 2024

Ganaxolone delivers sustained reductions in CDD-related seizures

16 Jan 2024

Treatment with ganaxolone in paediatric patients with cyclin-dependent kinase-like 5 deficiency disorder (CDD) leads to reductions in major motor seizure frequency (MMSF) over 2 years, according to data from the open-label extension phase of the Marigold trial.

Ganaxolone delivers sustained reductions in CDD-related seizures

16 Jan 2024

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Idiopathic Parkinson’s disease: Which dopamine agonist is associated with lower risk of impulse control–related behavioural disorders?

Idiopathic Parkinson’s disease: Which dopamine agonist is associated with lower risk of impulse control–related behavioural disorders?

Comorbid sleep-disordered breathing and AF poststroke linked to elevated mortality, recurrence

Comorbid sleep-disordered breathing and AF poststroke linked to elevated mortality, recurrence

Oxathridine linked to pseudohallucinations

Oxathridine linked to pseudohallucinations

Physical activity boosts mental health in young people with neurodevelopmental disorders

Physical activity boosts mental health in young people with neurodevelopmental disorders

Acupuncture shows promise for poststroke motor aphasia

Acupuncture shows promise for poststroke motor aphasia

Intracranial sinusitis complications may cause serious injury in children

Intracranial sinusitis complications may cause serious injury in children

Bacterial meningitis in childhood linked to long-term disabilities

Bacterial meningitis in childhood linked to long-term disabilities

Adding bevacizumab to chemo enhances antitumour activity in children with R/R neuroblastoma

Adding bevacizumab to chemo enhances antitumour activity in children with R/R neuroblastoma

Levetiracetam use during pregnancy poses no significant risks of birth defects, miscarriage

Levetiracetam use during pregnancy poses no significant risks of birth defects, miscarriage

Ganaxolone delivers sustained reductions in CDD-related seizures

Ganaxolone delivers sustained reductions in CDD-related seizures