Sirolimus reduces venous malformation size, eases GI bleeding in BRBNS
Oral sirolimus, also known as rapamycin, reduces the size of venous malformations (VMs), relieves gastrointestinal (GI) bleeding, and removes transfusion dependence of patients with blue rubber bleb nevus syndrome (BRBNS), results of a study have shown. Moreover, drug-related adverse effects are mild and typically self-limited.