News & Updates

COVID-19 vaccination adverse events rare in cancer patients

27 May 2022 by

A territory-wide cohort study of Hong Kong cancer patients finds a low incidence of adverse events of specific interest (AESI) following vaccination with two doses of either BNT162b2 or CZ02.

COVID-19 vaccination adverse events rare in cancer patients

27 May 2022

Combined therapy bests single modality in paediatric optic pathway gliomas

25 May 2022 by

Children with optic pathway gliomas (OPGs) fare better with a combination of treatments, as it leads to longer disease remission compared with single-modality treatment, as shown in a Singapore study.

Combined therapy bests single modality in paediatric optic pathway gliomas

25 May 2022

Preop radiotherapy, immediate reconstruction feasible in breast cancer patients

25 May 2022 by

Preoperative radiotherapy (preop RT), followed by skin-sparing mastectomy and immediate deep inferior epigastric perforator (DIEP) flap reconstruction, is technically feasible and safe in breast cancer patients who require mastectomy, the PRADA* trial suggests.

Preop radiotherapy, immediate reconstruction feasible in breast cancer patients

25 May 2022

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

23 May 2022

Poor outcomes are not significantly different in between patients with high-risk cutaneous squamous cell carcinomas treated with margin-negative resection only and those who underwent surgery with adjuvant radiotherapy, reveals a study.

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

23 May 2022

Cancer patients more vulnerable to PTSD during pandemic

23 May 2022

Cancer patients may be more susceptible to developing symptoms of post-traumatic stress disorder (PTSD), especially amid the COVID-19 pandemic, reports a recent study.

Cancer patients more vulnerable to PTSD during pandemic

23 May 2022

Prior faecal haemoglobin concentrations can help predict risk of future CRC, advanced neoplasia

21 May 2022

Prior faecal haemoglobin (F-Hb) concentrations are prognostic of the risk of developing colorectal cancer (CRC) or advanced neoplasia (AN), according to a study. When added to age and sex, prior F-Hb concentrations can accurately identify individuals at risk of the said diseases.

Prior faecal haemoglobin concentrations can help predict risk of future CRC, advanced neoplasia

21 May 2022

Tisagenlecleucel cost-effective for young adults with relapsed acute lymphoblastic leukaemia

20 May 2022 by

For young adults with relapsed/refractory acute lymphoblastic leukaemia (R/R ALL) who had failed at least two prior lines of therapies, tisagenlecleucel appears to be an inexpensive treatment option, according to a recent Singapore study.

Tisagenlecleucel cost-effective for young adults with relapsed acute lymphoblastic leukaemia

20 May 2022

Novel cellular therapy produces impressive responses in heavily pretreated CD30-positive lymphoma

19 May 2022 by

A novel cellular therapy that links the bispecific antibody AFM13 with cord blood–derived natural killer cells (AFM13-NK), when used at recommended phase II dose (RP2D), produces a 100 percent overall response rate (ORR) in patients with refractory or relapsed CD30-positive Hodgkin or non-Hodgkin lymphomas (HL/NHL), according to results of the NCT04074746 trial presented at American Association for Cancer Research (AACR) 2022.

Novel cellular therapy produces impressive responses in heavily pretreated CD30-positive lymphoma

19 May 2022

High BMI might promote MGUS progression to multiple myeloma

17 May 2022

In individuals with monoclonal gammopathy of undetermined significance (MGUS), obesity or high body mass index (BMI) seems to aggravate the risk of disease progression to multiple myeloma (MM), an effect that appears to be stronger in women, a recent study has found.

High BMI might promote MGUS progression to multiple myeloma

17 May 2022

Polygenic risk scores for hepatic fat, NAFLD pinpoint Asians at risk of HCC

17 May 2022 by

Both the polygenic risk score (PRS) for hepatic fat (HFC-PRS) derived from non-Asians and the novel PRS for nonalcoholic fatty liver disease (NAFLD) derived from East Asians can predict the incidence of hepatocellular carcinoma (HCC) in Singaporeans, as shown in a study.

Polygenic risk scores for hepatic fat, NAFLD pinpoint Asians at risk of HCC

17 May 2022

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COVID-19 vaccination adverse events rare in cancer patients

COVID-19 vaccination adverse events rare in cancer patients

Combined therapy bests single modality in paediatric optic pathway gliomas

Combined therapy bests single modality in paediatric optic pathway gliomas

Preop radiotherapy, immediate reconstruction feasible in breast cancer patients

Preop radiotherapy, immediate reconstruction feasible in breast cancer patients

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

Surgery plus radiotherapy no better than surgery alone in cutaneous squamous cell carcinoma

Cancer patients more vulnerable to PTSD during pandemic

Cancer patients more vulnerable to PTSD during pandemic

Prior faecal haemoglobin concentrations can help predict risk of future CRC, advanced neoplasia

Prior faecal haemoglobin concentrations can help predict risk of future CRC, advanced neoplasia

Tisagenlecleucel cost-effective for young adults with relapsed acute lymphoblastic leukaemia

Tisagenlecleucel cost-effective for young adults with relapsed acute lymphoblastic leukaemia

Novel cellular therapy produces impressive responses in heavily pretreated CD30-positive lymphoma

Novel cellular therapy produces impressive responses in heavily pretreated CD30-positive lymphoma

High BMI might promote MGUS progression to multiple myeloma

High BMI might promote MGUS progression to multiple myeloma

Polygenic risk scores for hepatic fat, NAFLD pinpoint Asians at risk of HCC

Polygenic risk scores for hepatic fat, NAFLD pinpoint Asians at risk of HCC