Tin tức & Cập nhật

Using small molecule drugs to modulate the cystic fibrosis transmembrane conductance regulator (CFTR) protein improves multiple aspects of cystic fibrosis in paediatric patients, including lung function, CFTR protein function, and nutritional status, according to a recent meta-analysis.

High-dose zinc supplementation was significantly associated with decreased feeding intolerance in very low birth weight (VLBW) preterm infants, according to a study presented at ESPGHAN 2022.

Inotuzumab ozogamicin is well tolerated and demonstrates clinical activity in children with relapsed or refractory acute lymphoblastic leukaemia (ALL), according to the results of a phase II trial.

The combination of two targeted therapies, dabrafenib and trametinib, significantly improves the overall response rate (ORR) in paediatric patients with low-grade glioma (LGG) with BRAF V600 mutations compared with the combination of standard chemotherapy drugs, according to a study presented at ASCO 2022.

The children’s module of the Bladder Scanner (BS), a portable ultrasound device used to measure bladder volume, shows acceptable accuracy in children 4 years of age and above, according to a recent study. However, device performance appears unreliable in younger children.

The delivery of nitric oxide into the cardiopulmonary bypass in young children undergoing surgery for congenital heart disease does not significantly reduce the number of ventilator-free days, as shown in a study.

The routine implementation of cerebral magnetic resonance imaging (cMRI) commonly detects low-grade abnormalities in extremely premature infants, such as low-grade intraventricular haemorrhage (IVH), white matter disease (WMD), and cerebellar injury (CBI), a new study has found.