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Supplementation with probiotics appears to induce an acute effect on reaction times during executive function, hinting at the possibility of preventing the development of depression among older adults, according to a study.

Probiotic supplement may improve cognition, mood in older adults

Low-dose morphine may do more harm than good for COPD patients with chronic breathlessness

Treatment with steady-state, low-dose morphine does not appear to improve sleep efficiency, sleep-disordered breathing frequency, or next-day alertness but may rather result in hypoventilation during sleep in chronic obstructive pulmonary disease (COPD) patients with chronic breathlessness, according to the results of a randomized, double-anonymized, crossover trial.

Low-dose morphine may do more harm than good for COPD patients with chronic breathlessness

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

14 Jun 2025 bởi

Maintenance treatment with vedolizumab proved safe and effective in paediatric inflammatory bowel disease (IBD), with long-term remission achieved more frequently in children with ulcerative colitis (UC) than in those with Crohn’s disease (CD), according to the final 3-year data from the VEDOKIDS study.

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

Insulinemic lifestyle pattern ups risk of endometrial cancer

A lifestyle pattern with higher insulinemic potential may predispose an individual to endometrial cancer (EC), suggests a study.

Insulinemic lifestyle pattern ups risk of endometrial cancer

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

Treatment with the combination of zanidatamab plus palbociclib and fulvestrant is safe and demonstrates promising antitumour activity in patients with HR-positive, HER2-positive advanced or metastatic breast cancer, according to a phase IIa study.

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

IBD tied to increased risk of rheumatoid arthritis

Patients with inflammatory bowel disease (IBD) appear to be at heightened risk of rheumatoid arthritis (RA), as reported in a study.

IBD tied to increased risk of rheumatoid arthritis

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

Both drotaverine and peppermint oil are safe and help alleviate abdominal pain in children whose pain cannot be attributed to a specific medical condition, with neither treatment demonstrating clear superiority over the other, according to the results of a single-blind, randomized controlled trial.

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

Ultrasensitive ctDNA detection predicts breast cancer relapse

A molecular residual disease (MRD) assay powered by whole genome sequencing (WGS) successfully detects breast cancer relapse, improving lead times for circulating tumour DNA (ctDNA) detection years ahead of clinical recurrence based on imaging.

Ultrasensitive ctDNA detection predicts breast cancer relapse

13 Jun 2025

Phone-based strategy supports BP control after a stroke

A nurse-led mobile health (mHealth) intervention that utilizes basic phones improves blood pressure (BP) control among stroke survivors in Ghana, as shown in the phase III PINGS-2 trial.

Phone-based strategy supports BP control after a stroke

Wearables fare well for AF detection