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Very low HBsAg levels predict HBsAg loss, disease remission after therapy cessation
Following discontinuation of nucleot(s)ide analogue therapy, only about one-third of patients with HBeAg-negative chronic hepatitis B (CHB) achieve disease remission, with rare HBsAg loss, as reported in a study. The likelihood of HBsAg loss and disease remission is high in the presence of very low HBsAg levels at baseline.
Postjab nAb assessment at one’s fingertips
A group of researchers from Singapore has recently developed a finger stick blood test that can rapidly and semi-quantitatively assess the neutralizing antibody (nAb) response of people who have been vaccinated against COVID-19.
MS patients on certain DMTs may have limited protection from COVID-19 vax
The overall rate of hospitalization for COVID-19 is low among patients with multiple sclerosis (MS) treated with disease-modifying therapies (DMTs) who have been vaccinated against COVID-19, according to a prospective study from England. However, patients on ocrelizumab or fingolimod have elevated hospitalization rates.
Infants with late-onset GBS develop sepsis, meningitis
Sepsis or septic shock and bacterial meningitis, which are associated with non-negligible morbidity and mortality, frequently occur in infants with group B Streptococcus (GBS) late-onset disease (LOD), reports a recent study.