Tin tức & Cập nhật

The investigational L-type amino acid transporter 1 inhibitor nanvuranlat has an acceptable safety profile and is associated with prolonged progression-free survival (PFS) in patients with advanced and refractory biliary tract cancer when used in later-line treatment settings, according to the results of a phase II study.

The extent of liver fibrosis appears to be higher among people living with HIV (PWH) who have metabolic dysfunction-associated steatotic liver disease (MASLD), despite lower NAFLD activity score (NAS) and less pronounced histological drivers of fibrosis, than among their counterparts who have no HIV, according to a study.

EF-hand domain family member D2 (EFHD2), a novel molecule specific to immune cells, plays a major immunomodulatory and inflammatory role in nonalcoholic steatohepatitis (NASH), reveals a study, noting how EFHD2 can be a promising target for NASH treatment.

The presence of nonalcoholic fatty liver disease (NAFLD) can impair the sexual function of premenopausal women, suggests a study in Egypt.

Use of aspirin appears to be beneficial in the prevention of pancreatic cancer, according to a study.

Among patients with metabolic dysfunction-associated fatty liver disease (MAFLD), those with lower serum concentrations of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein/zeaxanthin are at heightened risk of all-cause and cardiovascular mortality, according to a study.

The effect of certain dietary patterns on liver fat content (LFC) and iron-controlled T1 time (cT1, a measure of liver inflammation and fibrosis) may be elevated among patients who are at greater genetic risk for steatotic liver disease (SLD), suggests a study. This indicates that dietary interventions can be of benefit in this population.

Interactions exist between high-risk factors for thrombosis and new thrombotic events in patients with noncirrhotic portal vein thrombosis (NCPVT) with local factors, reports a study.