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Givosiran delivers safe, sustained improvements in acute hepatic porphyria

28 Nov 2023 bởi

Long-term monthly treatment with givosiran has good tolerability and offers continuous improvements to patients with acute hepatic porphyria (AHP), results of the phase III ENVISION trial have shown.

Givosiran delivers safe, sustained improvements in acute hepatic porphyria

28 Nov 2023

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

27 Nov 2023 bởi

A systematic review and meta-analysis by researchers from the University of Hong Kong has shown that the use of peripherally inserted central catheters (PICCs) is associated with a higher rate of complications than central lines in terminally ill cancer patients with central venous access devices (CVADs) for palliative care. No conclusions were reached regarding the use of totally implanted ports (PORTs), as no studies on PORTs were eligible for analysis.

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

27 Nov 2023

Novel tri-agonist confers significant gains for MASLD patients

24 Nov 2023 bởi

In a substudy of a phase II obesity trial, individuals with MASLD* and obesity benefited significantly from retatrutide, a once-weekly, injectable, novel synthetic molecule that has shown potent agonist action at GIP**, GLP-1***, and glucagon receptors.

Novel tri-agonist confers significant gains for MASLD patients

24 Nov 2023

Cholecystectomy during pregnancy supported in large study

24 Nov 2023

For expectant mothers with acute cholecystitis (AC), undergoing cholecystectomy lowers the risk of adverse pregnancy outcomes, according to a large study.

Cholecystectomy during pregnancy supported in large study

24 Nov 2023

Remnant cholesterol predicts NAFLD development

23 Nov 2023

Serum levels of remnant cholesterol may be used to assess an individual’s susceptibility to developing nonalcoholic fatty liver disease (NAFLD), independent of traditional lipid profiles, suggests a recent study.

Remnant cholesterol predicts NAFLD development

23 Nov 2023

HBV vaccine improves survival of patients with chronic liver disease

22 Nov 2023 bởi

Vaccination against hepatitis B virus (HBV) results in meaningful improvements in survival among patients with different kinds of chronic liver diseases, suggests a study presented at AASLD 2023.

HBV vaccine improves survival of patients with chronic liver disease

22 Nov 2023

Can elexacaftor/tezacaftor/ivacaftor cause liver damage in adults with cystic fibrosis?

21 Nov 2023 bởi

Treatment with elexacaftor/tezacaftor/ivacaftor (ETI) rarely results in severe drug-induced liver injury among adults with cystic fibrosis, as shown in a study presented at AASLD 2023. Moreover, serum markers of fibrosis have increased but remain within normal range.

Can elexacaftor/tezacaftor/ivacaftor cause liver damage in adults with cystic fibrosis?

21 Nov 2023

Bulevirtide-PegIFNα combo yields benefits for CHD patients

21 Nov 2023 bởi

A combination regimen comprising bulevirtide 10 mg (BLV10) and pegylated interferon alpha-2a (PegIFNα) improved multiple liver parameters in patients with chronic hepatitis delta (CHD), findings from the phase IIb MYR204 study have shown.

Bulevirtide-PegIFNα combo yields benefits for CHD patients

21 Nov 2023

8-week TAF course enough to prevent mother–child HBV transmission

20 Nov 2023 bởi

An 8-week course is as good as a 12-week course of tenofovir alafenamide fumarate (TAF) therapy in terms of preventing the transmission of hepatitis B virus (HBV) infection from mothers to infants, as reported in a study.

8-week TAF course enough to prevent mother–child HBV transmission

20 Nov 2023

Machine perfusion delivers positive outcomes for liver transplantation

18 Nov 2023

Machine perfusion techniques are effective and appear to be better than static cold storage (SCS) in patients who underwent liver transplantation, suggest the results of a meta-analysis.

Machine perfusion delivers positive outcomes for liver transplantation

18 Nov 2023

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Givosiran delivers safe, sustained improvements in acute hepatic porphyria

Givosiran delivers safe, sustained improvements in acute hepatic porphyria

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

Palliative care in cancer: Which central venous access devices are associated with higher complication rates?

Novel tri-agonist confers significant gains for MASLD patients

Novel tri-agonist confers significant gains for MASLD patients

Cholecystectomy during pregnancy supported in large study

Cholecystectomy during pregnancy supported in large study

Remnant cholesterol predicts NAFLD development

Remnant cholesterol predicts NAFLD development

HBV vaccine improves survival of patients with chronic liver disease

HBV vaccine improves survival of patients with chronic liver disease

Can elexacaftor/tezacaftor/ivacaftor cause liver damage in adults with cystic fibrosis?

Can elexacaftor/tezacaftor/ivacaftor cause liver damage in adults with cystic fibrosis?

Bulevirtide-PegIFNα combo yields benefits for CHD patients

Bulevirtide-PegIFNα combo yields benefits for CHD patients

8-week TAF course enough to prevent mother–child HBV transmission

8-week TAF course enough to prevent mother–child HBV transmission

Machine perfusion delivers positive outcomes for liver transplantation

Machine perfusion delivers positive outcomes for liver transplantation