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Methylnaltrexone proves safety in paediatric oncology patients with constipation
Subcutaneous methylnaltrexone is safe to use in children with cancer who have opioid-induced constipation, suggest the results of a study. In addition, this agent stimulates bowel movements in more than a third of paediatric patients.

TRT boosts sexual function, eases symptoms in men with hypogonadism
Testosterone replacement therapy (TRT) can help increase sexual activity, improve hypogonadal symptoms, and boost sexual desire among middle-aged and older men with hypogonadism and low libido, reports a study. However, TRT does not improve erectile function.

Infliximab, vedolizumab similarly effective as 1L Tx for paediatric IBD
In a study presented at Crohn’s and Colitis Congress 2024, infliximab and vedolizumab were found to have similar effectiveness in achieving steroid-free clinical remission (SFCR) and biochemical remission (BR) at 12 months when used as first-line treatment for biologic-naïve paediatric patients with uncomplicated mild-to-moderately active inflammatory bowel disease (IBD).






