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Add-on tiragolumab improves antitumour response in unresectable HCC

03 Feb 2025

In the treatment of patients with unresectable hepatocellular carcinoma (HCC), the addition of tiragolumab to atezolizumab plus bevacizumab yields meaningful improvements in antitumour response and disease control, according to data from an open-label phase 1b–2 study.

Add-on tiragolumab improves antitumour response in unresectable HCC

03 Feb 2025

Experimental HPV vaccine shrinks high-grade precancerous cervical lesions

02 Feb 2025 bởi

A novel vaccine that targets HPV type 16 (HPV16) has shown clinical activity against HPV16-positive cervical intraepithelial neoplasia grade 3 (CIN3) in a phase II trial, substantially reducing lesion size.

Experimental HPV vaccine shrinks high-grade precancerous cervical lesions

02 Feb 2025

Does sacubitril-valsartan plus spironolactone induce ADRs?

02 Feb 2025

Treatment with the combination of sacubitril-valsartan plus spironolactone during hospitalization for acute decompensated heart failure (ADHF) does not lead to a substantially higher incidence of adverse drug reactions (ADRs), a study has shown.

Does sacubitril-valsartan plus spironolactone induce ADRs?

02 Feb 2025

Abnormal body weight in adolescence a risk factor for infertility in Asian women

02 Feb 2025

Underweight or obesity during adolescence may contribute to unexplained infertility later in life, as suggested in a large study involving Japanese women.

Abnormal body weight in adolescence a risk factor for infertility in Asian women

02 Feb 2025

Baricitinib plus phototherapy shows potential against extensive vitiligo

01 Feb 2025

Treatment with the combination of the small molecule Janus kinase 1/2 inhibitor baricitinib plus phototherapy may help reduce disease activity and induce repigmentation in adults with extensive and active nonsegmental vitiligo, according to the results of a phase II study.

Baricitinib plus phototherapy shows potential against extensive vitiligo

01 Feb 2025

Antipsychotic adherence helps keep lid on suicidal behaviour

01 Feb 2025 bởi

Ensuring antipsychotic medication use as prescribed may be crucial for reducing the risk of suicidality among patients with schizophrenia, according to a study.

Antipsychotic adherence helps keep lid on suicidal behaviour

01 Feb 2025

Clozapine tied to haematological malignancy in schizophrenia

01 Feb 2025 bởi

The use of clozapine appears to slightly increase the risk of haematological malignancy (HM) among patients with schizophrenia compared with olanzapine use, suggests a study.

Clozapine tied to haematological malignancy in schizophrenia

01 Feb 2025

Laparoscopic noninferior to open surgery for low rectal cancer

01 Feb 2025

The disease-free survival outcome in patients with low rectal cancer who receive laparoscopic surgery compares favourably with that in those who receive open surgery, according to a study.

Laparoscopic noninferior to open surgery for low rectal cancer

01 Feb 2025

Prourokinase does not improve functional outcomes in mild ischaemic stroke

31 Jan 2025

In the treatment of patients with mild ischaemic stroke, prourokinase is not necessarily better than standard of care in terms of improving functional outcomes, although both have a similar safety profile, according to a study.

Prourokinase does not improve functional outcomes in mild ischaemic stroke

31 Jan 2025

Electrospun fibre patch to simplify psoriasis treatment

31 Jan 2025 bởi

A new patch that adheres to the skin and delivers two active ingredients holds promise in the treatment of psoriasis, reducing the need to apply topical medications to once a day and potentially improving adherence.

Electrospun fibre patch to simplify psoriasis treatment

31 Jan 2025

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Add-on tiragolumab improves antitumour response in unresectable HCC

Add-on tiragolumab improves antitumour response in unresectable HCC

Experimental HPV vaccine shrinks high-grade precancerous cervical lesions

Experimental HPV vaccine shrinks high-grade precancerous cervical lesions

Does sacubitril-valsartan plus spironolactone induce ADRs?

Does sacubitril-valsartan plus spironolactone induce ADRs?

Abnormal body weight in adolescence a risk factor for infertility in Asian women

Abnormal body weight in adolescence a risk factor for infertility in Asian women

Baricitinib plus phototherapy shows potential against extensive vitiligo

Baricitinib plus phototherapy shows potential against extensive vitiligo

Antipsychotic adherence helps keep lid on suicidal behaviour

Antipsychotic adherence helps keep lid on suicidal behaviour

Clozapine tied to haematological malignancy in schizophrenia

Clozapine tied to haematological malignancy in schizophrenia

Laparoscopic noninferior to open surgery for low rectal cancer

Laparoscopic noninferior to open surgery for low rectal cancer

Prourokinase does not improve functional outcomes in mild ischaemic stroke

Prourokinase does not improve functional outcomes in mild ischaemic stroke

Electrospun fibre patch to simplify psoriasis treatment

Electrospun fibre patch to simplify psoriasis treatment