Tin tức & Cập nhật

Treatment with the acetylcholinesterase inhibitor donepezil hydrochloride falls short of improving post–COVID-19 conditions such as fatigue and psychological symptoms, as shown in a study from Japan.

In adults with virologically suppressed HIV-1* infection, switching to a two-drug regimen of doravirine 100 mg and islatravir 0.25 mg (DOR/ISL) was noninferior to continuing bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) or other baseline antiretroviral therapy (bART) regimens in maintaining viral suppression at 48 weeks, according to two phase III trials presented at CROI 2025. 

COVID-19 led to more severe disease outcomes than influenza or respiratory syncytial virus (RSV) during the 2022–2023 season, whereas the differences were attenuated in the subsequent season, as shown in a retrospective study.

Use of the monoclonal antibody sotrovimab within 10 days of COVID-19 diagnosis appears to reduce the risk of hospitalization, mortality, and need for respiratory support in patients at high risk of progression to severe illness, according to large real-world data.

Increasing D-dimer is a useful predictor of negative clinical outcomes among individuals with invasive infections driven by Neisseria Meningitidis, suggests a study.