Lọc theo
In the frontline treatment of patients with HER2-expressing locally advanced or metastatic urothelial cancer, the combination of disitamab vedotin plus toripalimab yields a clinically meaningful and significant increase in survival compared with chemotherapy, as shown in the phase III RC48-C016 trial.
Lowering the systolic blood pressure (SBP) target to <120 mm Hg compared with <140 mm Hg has a beneficial effect on retinal microvasculature among hypertensive patients with high cardiovascular risk, suggests a recent study.
People with increased sun exposure during their adolescence and early adulthood appear to have a lower risk of breast cancer, as suggested in a population-based case-control study from Iran.
In the treatment of patients with developmental and epileptic encephalopathies (DEEs), the selective serotonin 5-HT2C receptor agonist bexicaserin is well tolerated and appears to reduce the frequency of countable motor seizures, according to a phase Ib/IIa study.
Individuals with SARS‐CoV‐2 infection, especially those who are hospitalized, face long‐term declines in left ventricular ejection fraction (LVEF), according to a retrospective study.
In patients with Parkinson’s disease (PD), the high risk of mild cognitive impairment (MCI) at the time of diagnosis correlates with low levels of plasma triglycerides (P-TG) and an interaction between change in BMI and P-TG prior to diagnosis, reports a study.
Older adults with frailty are predisposed to atrial fibrillation (AF)-related hospitalizations, regardless of the presence of multimorbidity, according to a study.
Individuals exposed to brighter lights at night have increased risks of incident coronary artery disease, myocardial infarction, heart failure, atrial fibrillation, and stroke, according to a study.
For patients who are struggling to lose weight after metabolic bariatric surgery, treatment with liraglutide boosts weight-loss outcomes and helps avoid conversion surgery, as shown in a randomized clinical trial.
The reduction in relative risk with intensive vs standard systolic blood pressure (SBP) treatment among individuals without baseline cardiovascular disease (CVD) is consistent across the risk strata using the PREVENT* equations, as shown in the SPRINT study.
