Tin tức & Cập nhật

Selpercatinib, a highly selective and potent RET inhibitor, trumped two multikinase inhibitors (MKIs) – cabozantinib and vandetanib – for the treatment of advanced, kinase inhibitor-naïve, RET-mutant medullary thyroid cancer (MTC) in the first-line (1L) setting, according to the interim analysis results of the phase III LIBRETTO-531 trial.

Use of apixaban appears to reduce the risk of gastrointestinal haemorrhage (GIH) compared with dabigatran, rivaroxaban, and vitamin K antagonist (VKA) in patients with nonvalvular atrial fibrillation, a recent study has shown. On the other hand, rivaroxaban use tends to increase GIH risk relative to dabigatran and VKA.

Several factors are directly associated with either an increase or a decrease of pharmacokinetic parameters of doxorubicin, reports a recent study.

Older age, lower skin phototype classifications, and a personal history of skin cancer may influence the severity of actinic keratosis (AK), while the use of calcium channel blockers (CCBs) is linked to more severe AK, as reported in a study.

Podcast: Professor Flor Munoz discusses the importance of vaccination for pregnant women and children against COVID-19 at IDWeek 2023

Podcast: Professor Gregory Poland discusses updates on the development of RSV vaccines at IDWeek 2023