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Antivirals underutilized after curative resection of HBV- or HCV-related HCC

15 Jan 2024 bởi

Antiviral therapy is associated with substantial improvements in long-term overall survival (OS) but severely underutilized after curative hepatic resection in patients with hepatitis B virus (HBV)– or hepatitis C virus (HCV)–related hepatocellular carcinoma (HCC), a real-world study involving predominantly Asian patients has shown.

Antivirals underutilized after curative resection of HBV- or HCV-related HCC

15 Jan 2024

$Patients with autoimmune hepatitis at higher risk of osteoporotic fracture$

Patients with autoimmune hepatitis at higher risk of osteoporotic fracture

12 Jan 2024

The risk of osteoporotic fracture seems greater in patients with autoimmune hepatitis (AIH), reveals a recent study. In addition, those with cirrhosis and long-term use of glucocorticoids appear to be at much greater risk.

Patients with autoimmune hepatitis at higher risk of osteoporotic fracture

12 Jan 2024

Fibrosis screening prompts positive lifestyle shifts

05 Jan 2024

Screening for liver fibrosis appears to spur lifestyle improvements especially among people who screened positive for the condition, according to a study.

Fibrosis screening prompts positive lifestyle shifts

05 Jan 2024

Aspirin reduces liver fat, improves markers of inflammation, fibrosis

04 Jan 2024 bởi

Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) – previously called nonalcoholic fatty liver disease (NAFLD) – but without cirrhosis, who were treated with daily low-dose aspirin, had significant reductions in liver fat for 6 months in a new trial.

Aspirin reduces liver fat, improves markers of inflammation, fibrosis

04 Jan 2024

NAFLD ups risk of memory impairment, hippocampal damage

20 Dec 2023

The presence and severity of nonalcoholic fatty liver disease (NAFLD) may contribute to cognitive impairment, as well as hippocampal structure and functional abnormalities, suggests a study.

NAFLD ups risk of memory impairment, hippocampal damage

20 Dec 2023

Original New Drug Application Approvals by US FDA (16-30 November 2023)

13 Dec 2023

New drug applications approved by US FDA as of 16-30 November 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-30 November 2023)

13 Dec 2023

NAFLD progression may raise ESLD risk

13 Dec 2023

Histological disease progression in patients with nonalcoholic fatty liver disease (NAFLD) is significantly associated with a higher rate of developing incident end-stage liver disease (ESLD) but not with all-cause mortality, a study has shown.

NAFLD progression may raise ESLD risk

13 Dec 2023

AFP-L3, DCP predict HCC recurrence after liver transplant

13 Dec 2023

Dual positivity for alpha-fetoprotein (AFP) bound to Lens culinaris agglutinin (AFP-L3) ≥15 percent and des-gamma-carboxyprothrombin (DCP) ≥7.5 can strongly predict majority of early hepatocellular carcinoma (HCC) recurrences following liver transplantation (LT), suggests a study.

AFP-L3, DCP predict HCC recurrence after liver transplant

13 Dec 2023

Molecular-based guided therapy shows promise in treatment-resistant HCC/H-CCK

12 Dec 2023

A recent study has demonstrated the feasibility of molecular-based targeted therapy in patients with hepatocellular carcinoma (HCC)/hepato-cholangiocarcinoma (H-CCK) that progressed while under treatment with atezolizumab/bevacizumab.

Molecular-based guided therapy shows promise in treatment-resistant HCC/H-CCK

12 Dec 2023

Resmetirom reduces bad cholesterol, restores thyroid hormones in NASH

12 Dec 2023 bởi

Treatment with resmetirom significantly reduced low-density lipoprotein cholesterol (LDL-C) and other atherogenic lipids, as well as restored thyroid hormone (TH) levels in patients with nonalcoholic steatohepatitis (NASH), according to two subgroup analyses of the MAESTRO-NASH trial presented at The Liver Meeting 2023.

Resmetirom reduces bad cholesterol, restores thyroid hormones in NASH

12 Dec 2023

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Antivirals underutilized after curative resection of HBV- or HCV-related HCC

Antivirals underutilized after curative resection of HBV- or HCV-related HCC

Patients with autoimmune hepatitis at higher risk of osteoporotic fracture

Patients with autoimmune hepatitis at higher risk of osteoporotic fracture

Fibrosis screening prompts positive lifestyle shifts

Fibrosis screening prompts positive lifestyle shifts

Aspirin reduces liver fat, improves markers of inflammation, fibrosis

Aspirin reduces liver fat, improves markers of inflammation, fibrosis

NAFLD ups risk of memory impairment, hippocampal damage

NAFLD ups risk of memory impairment, hippocampal damage

Original New Drug Application Approvals by US FDA (16-30 November 2023)

Original New Drug Application Approvals by US FDA (16-30 November 2023)

NAFLD progression may raise ESLD risk

NAFLD progression may raise ESLD risk

AFP-L3, DCP predict HCC recurrence after liver transplant

AFP-L3, DCP predict HCC recurrence after liver transplant

Molecular-based guided therapy shows promise in treatment-resistant HCC/H-CCK

Molecular-based guided therapy shows promise in treatment-resistant HCC/H-CCK

Resmetirom reduces bad cholesterol, restores thyroid hormones in NASH

Resmetirom reduces bad cholesterol, restores thyroid hormones in NASH