Tin tức & Cập nhật

Use of teduglutide is effective against short bowel syndrome (SBS) in paediatric patients, although some children need a longer duration of treatment to achieve enteral autonomy, according to a Spain study presented at ESPGHAN 2023. Predictive factors of response to treatment have not been identified.

Treatment with dupilumab significantly improves histologic and endoscopic measures of eosinophilic esophagitis (EoE) in young children aged 1–11 years, according to the phase III EoE KIDS trial presented at ESPGHAN 2023.

Treatment with sacubitril/valsartan appears to be better than valsartan alone in reversing ventricular remodeling in perimenopausal hypertensive women, suggests a study.

Treatment with methotrexate (MTX) does not appear to be associated with testicular toxicity, according to the results of the iFAME-MTX study, dispelling concerns about the effect of the drugs among men wishing to become a parent and their clinicians.

Use of nonprescription drugs loperamide and mitragynine appears to contribute to the risk of life-threatening ventricular arrhythmia, reports a study in North America.

A case-control surveillance study has found no link between monovalent COVID-19 boosters and miscarriage before 20 weeks of pregnancy.

Adding the probiotic Limosilactobacillus reuteri (L. reuteri) DSM 17938 to antibiotic therapy significantly reduced the incidence of antibiotic-associated diarrhoea (AAD) in children with acute otitis media or acute bacterial sinusitis in the PEARL study presented at ESPGHAN 2023.

Interim results from the ongoing Study 306, a phase III open-label trial, show improved immunogenicity and safety of the bivalent Omicron-containing mRNA-1273.214 vaccine in children 6 months to 5 years of age, both as a primary series and a booster.