Tin tức & Cập nhật

Induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) appears promising in its capacity to increase overall survival (OS) among patients with T3-4N0-1 nasopharyngeal carcinoma (NPC) compared with CCRT alone, suggests a recent study in China.

Revumenib, a novel potent, selective oral inhibitor of the menin-KMT2A interaction, demonstrated promising antileukaemic activity in children and adults with highly refractory acute leukaemia with KMT2Ar* or NPM1* mutation, a phase I dose-escalation study finds.

The use of vaginal estrogen in women with estrogen deficiency appears to reduce the likelihood of urinary tract infection (UTI) recurring, according to a study.

A single dose of nirsevimab administered before or during the respiratory syncytial virus (RSV) season provides protection against RSV lower respiratory tract infection (LRTI) hospitalization and very severe infection in infants, according to the preliminary results of a clinical trial conducted in real-world settings.

Children with Lennox-Gastaut syndrome (LGS) and Dravet's syndrome (DS) achieve improvements in both seizure management and nonseizure outcomes following treatment with cannabidiol (CBD)—a success echoed in their adult counterparts, as shown in a study presented at AAN 2023.

Use of dexmedetomidine has lessened the effective concentration (EC50) of propofol administered via plasma target-controlled infusion (TCI) during gastrointestinal endoscopy, a study has found. A 0.5‒1 μg/kg dose of dexmedetomidine results in a lower heart rate (HR) without bradycardia.

Induction therapy with guselkumab, an interleukin-23 p19 subunit antagonist, results in clinical and symptomatic remission, as well as other endoscopic improvements in patients with moderate-to-severe active ulcerative colitis (UC), according to the QUASAR study presented at DDW 2023.