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Novel neutralizing mAb offers potential treatment for cerebral ischaemic injury

02 Apr 2024 bởi

Researchers from a joint team at the University of Hong Kong (HKU) and Chinese Academy of Sciences have developed a novel neutralizing monoclonal antibody (mAb; 6H2) that targets circulating adipocyte fatty acid–binding protein (A-FABP), offering potential in alleviating cerebral ischaemic injury.

Novel neutralizing mAb offers potential treatment for cerebral ischaemic injury

02 Apr 2024

Renal denervation affords durable BP control

02 Apr 2024

Renal denervation yields substantial reductions in ambulatory systolic blood pressure for up to 36 years in randomized controlled trials and up to 10 years in observational cohort studies without compromising renal function, according to the results of a systematic review and meta-analysis.

Renal denervation affords durable BP control

02 Apr 2024

Prenatal topiramate not associated with autism in offspring

02 Apr 2024 bởi

Prenatal exposure to topiramate does not increase the risk of autism in offspring, a US nationwide cohort study has shown.

Prenatal topiramate not associated with autism in offspring

02 Apr 2024

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

02 Apr 2024 bởi

Adding pembrolizumab to standard chemotherapy resulted in a favourable overall survival (OS) benefit in patients with advanced or recurrent endometrial cancer compared with chemotherapy alone, regardless of mismatch repair (MMR) status, according to a key prespecified secondary analysis of the NRG-GY018 trial presented at the SGO 2024.

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

02 Apr 2024

Edoxaban matches apixaban for stroke prevention in very elderly population

01 Apr 2024

Very elderly patients with nonvalvular atrial fibrillation fare well with either edoxaban or apixaban in terms of stroke prevention, although those on edoxaban may have higher bleeding risk, according to a study.

Edoxaban matches apixaban for stroke prevention in very elderly population

01 Apr 2024

Plasma caffeine concentrations tied to reduced IBD risk

01 Apr 2024

A recent study has found that genetically predicted higher plasma caffeine concentrations can lower the risk of inflammatory bowel disease (IBD), including its subtypes.

Plasma caffeine concentrations tied to reduced IBD risk

01 Apr 2024

COVID vaccine hesitancy linked to traffic crashes

01 Apr 2024

People who refused to be vaccinated against COVID-19 appear to be at significantly greater risks of a traffic accident, reports a study.

COVID vaccine hesitancy linked to traffic crashes

01 Apr 2024

Unhealthy diet prevalent in childhood cancer survivors

01 Apr 2024

Many adult survivors of childhood cancer do not adhere to a healthful dietary pattern, particularly racial minorities and those with a lower socioeconomic status, reveals a study.

Unhealthy diet prevalent in childhood cancer survivors

01 Apr 2024

Oral minocycline flops for geographic atrophy in AMD

01 Apr 2024

Treatment with oral minocycline falls short of slowing the rate of geographic atrophy (GA) enlargement in patients with age-related macular degeneration (AMD), according to the results of a phase II study.

Oral minocycline flops for geographic atrophy in AMD

01 Apr 2024

$Preop skin antiseptic in fracture fixation: Which is better?$

Preop skin antiseptic in fracture fixation: Which is better?

01 Apr 2024 bởi

In patients undergoing fixation of a closed lower limb or pelvic fracture, iodine povacrylex in alcohol appears to be a better option than chlorhexidine gluconate (CHG) in alcohol as preoperative skin antiseptic to prevent surgical site infection (SSI). Among those with open upper limb or lower limb fracture, outcomes were similar for both solutions, the PREPARE* trial suggests.

Preop skin antiseptic in fracture fixation: Which is better?

01 Apr 2024

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Novel neutralizing mAb offers potential treatment for cerebral ischaemic injury

Novel neutralizing mAb offers potential treatment for cerebral ischaemic injury

Renal denervation affords durable BP control

Renal denervation affords durable BP control

Prenatal topiramate not associated with autism in offspring

Prenatal topiramate not associated with autism in offspring

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

Edoxaban matches apixaban for stroke prevention in very elderly population

Edoxaban matches apixaban for stroke prevention in very elderly population

Plasma caffeine concentrations tied to reduced IBD risk

Plasma caffeine concentrations tied to reduced IBD risk

COVID vaccine hesitancy linked to traffic crashes

COVID vaccine hesitancy linked to traffic crashes

Unhealthy diet prevalent in childhood cancer survivors

Unhealthy diet prevalent in childhood cancer survivors

Oral minocycline flops for geographic atrophy in AMD

Oral minocycline flops for geographic atrophy in AMD

Preop skin antiseptic in fracture fixation: Which is better?

Preop skin antiseptic in fracture fixation: Which is better?