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Progesterone flops for miscarriage, preterm birth prevention in PREEMPT
In pregnant women who present with first-trimester vaginal bleeding, treatment with progesterone throughout pregnancy does not appear to be beneficial in terms of lowering the risk of miscarriage or premature delivery, according to PREEMPT trial presented at this year’s American College of Obstetricians and Gynecologists (ACOG 2022) meeting.
SWOG S1616 suggests PFS benefit with ipi-nivo combo in metastatic/unresectable melanoma
The combination of ipilimumab and nivolumab may provide a progression-free survival (PFS) benefit in patients with metastatic or unresectable melanoma who did not respond to anti-PD-1/anti-PD-L1 therapy, according to a small study presented at AACR 2022.
Early remdesivir shields transplant recipients against life-threatening COVID-19
In solid organ transplant recipients with moderate symptoms of SARS-CoV-2 infection, early administration of a 3-day remdesivir course appears to effectively prevent COVID-19-related hospitalization as well as the clinical worsening of those who are hospitalized, according to a study.
Foetal risk low in LMWH-exposed women during pregnancy
Pregnant women with preconception venous thromboembolism (VTE) who have no exposure to any anticoagulant and those on low-molecular-weight heparin (LMWH) have the lowest risk of foetal adverse outcomes, reveals a study, which supports the recommendation of LMWH during pregnancy.