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Idiopathic Parkinson’s disease: Which dopamine agonist is associated with lower risk of impulse control–related behavioural disorders?
In Chinese patients with idiopathic Parkinson’s disease (IPD) on their first dopamine agonist (DA) monotherapy for >6 months, bromocriptine is associated with a lower risk of impulse control–related behavioural disorders (ICRDs) compared with pramipexole and ropinirole, an observational cohort study in Hong Kong has shown. Rotigotine demonstrated a trend towards lower ICRD risk than the latter two DAs.

Perinatal depression raises risk of death in women
Women who have been clinically diagnosed with perinatal depression are at greater risk of death, particularly during the first year of diagnosis and due to an unnatural death, such as suicide, reports a study. The observed association exists independent of psychiatric history and familiar factors.

Trazodone, CBT for insomnia only as good as placebo in haemodialysis patients
Cognitive behavioural therapy for insomnia (CBT-I) or trazodone appear to be no better than placebo in the treatment of insomnia among patients undergoing long-term haemodialysis, reveals a study. In addition, trazodone use is associated with a higher incidence of serious adverse events (SAEs).





